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Walking with a powered ankle-foot orthosis: the effects of actuation timing a...
Abstract Background In the last decades, several powered ankle-foot orthoses have been developed to assist the ankle joint of their users during walking. Recent studies have... -
The NuA4 acetyltransferase and histone H4 acetylation promote replication rec...
Abstract Background Histone acetylation plays an important role in DNA replication and repair because replicating chromatin is subject to dynamic changes in its structures.... -
Narcissistic traits in young people: understanding the role of parenting and ...
Abstract Background Elevated narcissism in young people often sets up a cascade of interpersonal and mental health challenges, reinforcing the need to understand its... -
Improving squalene production by enhancing the NADPH/NADP+ ratio, modifying t...
Abstract Background Squalene is currently used widely in the food, cosmetics, and medicine industries. It could also replace petroleum as a raw material for fuels. Microbial... -
The respiratory pressure—abdominal volume curve in a porcine model
Abstract Background Increasing intra-abdominal volume (IAV) can lead to intra-abdominal hypertension (IAH) or abdominal compartment syndrome. Both are associated with raised... -
Building damage survey and microtremor measurements for the source region of ...
Abstract We performed a damage survey of buildings and carried out microtremor observations in the source region of the 2015 Gorkha earthquake. Our survey area spans the... -
Predictors of the use of analgesic drugs 1 year after joint replacement: a si...
Abstract Background Pain persists in a moderate number of patients following hip or knee replacement surgery. Persistent pain may subsequently lead to the prolonged consumption... -
Computer use at work is associated with self-reported depressive and anxiety ...
Abstract Background With the development of technology, extensive use of computers in the workplace is prevalent and increases efficiency. However, computer users are facing new... -
A qualitative study of carers’ experiences of dementia cafés: a place to feel...
Abstract Background Unpaid, informal carers or caregivers play an important role in supporting people living with dementia but the role can be challenging and carers themselves... -
Onset, timing, and exposure therapy of stress disorders: mechanistic insight ...
Abstract Background The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine system that regulates numerous physiological processes. Disruptions in the activity of the... -
Long-term prenatal exposure to paracetamol is associated with DNA methylation...
Abstract Background Epidemiological studies have shown that long-term exposure to paracetamol during pregnancy is associated with attention-deficit/hyperactivity disorder... -
Fostering teaching-learning through workplace based assessment in postgraduat...
Abstract Background The principle of workplace based assessment (WBA) is to assess trainees at work with feedback integrated into the program simultaneously. A student driven... -
Intraflagellar transport proteins are involved in thrombocyte filopodia forma...
Intraflagellar transport (IFT) proteins are vital for the genesis and maintenance of cilia. Our identification of ift122 transcripts in zebrafish thrombocytes that lack primary... -
Analysis of SARS-CoV-2 RNA-dependent RNA polymerase as a potential therapeuti...
Abstract Background The Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) outbreak originating in Wuhan, China, has raised global health concerns and the... -
Microbial community shifts elicit inflammation in the caecal mucosa via the G...
Abstract Background Dietary structure in ruminants is closely connected with the composition of gastrointestinal microbiota. Merging study has shown that dietary induced SARA... -
When is enough, enough? Understanding and solving your sample size problems i...
Abstract Health services researchers face two obstacles to sample size calculation: inaccessible, highly specialised or overly technical literature, and difficulty securing... -
Resveratrol Binding to Human Complement fragment 5a (<sup>h</sup>C5a) may Mod...
Resveratrol (RSV), the active pharmaceutical ingredient (API) found in several fruits, nuts and marketed nutraceuticals is one of the promiscuous phytoalexin known to promote... -
DNA replication stress: a source of APOBEC3B expression in breast cancer
Abstract APOBEC cytidine deaminases have been implicated as major contributors to the mutation burden in many cancers on the basis of their mutational signature. A new... -
The development of the PARENTS: a tool for parents to assess residents’ non-t...
Abstract Background Parents can assess residents’ non-technical skills (NTS) in pediatric emergency departments (EDs). There are no assessment tools, with validity evidence, for... -
5G wireless P2MP backhaul security protocol: an adaptive approach
Abstract 5G has introduced various emerging demands for new services and technologies that raised the bar for quality of service, latency, handovers, and data rates. Such...
