762 items found

Types: other Groups: Datacite Tags: 110309 Infectious Diseases Biotechnology Pharmacology

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    Anti-malarial treatment outcomes in Ethiopia: a systematic review and meta-an...

    Abstract Background Ethiopia is among countries with a high malaria burden. There are several studies that assessed the efficacy of anti-malarial agents in the country and this...
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    Identifying targets for antibiotic stewardship interventions through analysis...

    Abstract Background In order to change antibiotic prescribing behaviour, we need to understand the prescribing process. The aim of this study was to identify targets for...
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    Repeated praziquantel treatment and Opisthorchis viverrini infection: a popul...

    Abstract Background Opisthorchis viverrini infection is highly prevalent in northeast Thailand. This liver fluke is classified as a carcinogen due to its causal links with...
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    A pilot feasibility randomised controlled trial of an adjunct brief social ne...

    Abstract Background Approximately 3% of people receiving opioid substitution therapy (OST) in the UK manage to achieve abstinence from prescribed and illicit drugs within three...
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    The Video intervention to Inspire Treatment Adherence for Life (VITAL Start):...

    Abstract Background Improving maternal antiretroviral therapy (ART) retention and adherence is a critical challenge facing prevention of mother-to-child transmission (PMTCT) of...
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    Risk factors for tuberculosis smear non-conversion in Eden district, Western ...

    Abstract Background Tuberculosis (TB) continues to be a major global health problem. While progress has been made to improve TB cure rates, South Africa’s 76 % smear-positive...
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    Patient’s perception of kidney stone prevention within the emergency departme...

    Abstract Background No known data in the literature assessing practice of kidney stone prevention in the emergency department (ED) is available. Objectives Assess patient...
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    User survey finds rapid evidence reviews increased uptake of evidence by Vete...

    Abstract Background To provide evidence synthesis for faster-paced healthcare decision-making, rapid reviews have emerged as a streamlined alternative to standard systematic...
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    Prevalence and social determinants of psychological distress among people who...

    Abstract Background People who use drugs are at a disproportionately higher risk of mental disorders due to prolonged exposure to psychosocial challenges. However, studies on...
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    UK national clinical audit: management of pregnancies in women with HIV

    Abstract Background The potential for HIV transmission between a pregnant woman and her unborn child was first recognized in 1982. Since then a complex package of measures to...
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    Using predicate and provenance information from a knowledge graph for drug ef...

    Abstract Background Biomedical knowledge graphs have become important tools to computationally analyse the comprehensive body of biomedical knowledge. They represent knowledge...
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    Comparison of anti-malarial drugs efficacy in the treatment of uncomplicated ...

    Abstract Background Artemisinin-based combination therapy (ACT) and novel drug combinations are available and used in African countries to treat uncomplicated malaria. Network...
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    A systematic review of clinical audit in companion animal veterinary medicine

    Abstract Background Clinical audit is a quality improvement process with the goal of continuously improving quality of patient care as assessed by explicit criteria. In human...
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    HIV-1 integrase resistance associated mutations and the use of dolutegravir i...

    Abstract Background Sub-Saharan Africa carries the greatest burden of HIV-infection with increasing drug resistance burden, which requires improved patient management and...
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    An interview study of pregnant women who were provided with indoor air qualit...

    Abstract Background Maternal smoking can cause health complications in pregnancy. Particulate matter (PM2.5) metrics applied to second hand smoke (SHS) concentrations provide...
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    Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate...

    Abstract Background Dexketoprofen trometamol plus tramadol hydrochloride is a new oral combination of two analgesics, which have different mechanisms of action for the treatment...
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    A systematic review of non-antibiotic measures for the prevention of urinary ...

    Abstract Background Urinary tract infections (UTIs) are common in pregnancy and account for the highest proportion of primary care antibiotic prescriptions issued to pregnant...
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    Development of a core outcome set for diabetes after pregnancy prevention int...

    Abstract Background Gestational diabetes mellitus (GDM) increases the risk of adverse short- and long-term outcomes, including development of type 2 diabetes. The US Diabetes...
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    Removal of the product from the culture medium strongly enhances free fatty a...

    Abstract Background Cyanobacterial mutants engineered for production of free fatty acids (FFAs) secrete the products to the medium and hence are thought to be useful for biofuel...
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    Development of a core outcome set for clinical trials in facial aging: study ...

    Abstract Background Facial aging is a concern for many patients. Wrinkles, loss of volume, and discoloration are common physical manifestations of aging skin. Genetic heritage,...