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Novel mutation in the CHST6 gene causes macular corneal dystrophy in a black ...
Abstract Background Macular corneal dystrophy (MCD) is a rare autosomal recessive disorder that is characterized by progressive corneal opacity that starts in early childhood... -
Temperature-dependent Crystallization of MoS2 Nanoflakes on Graphene Nanoshee...
Abstract This work primarily studies the crystallization condition of molybdenum disulfide (MoS2) in MoS2/graphene hybrids by a temperature-varying hydrothermal method from 150... -
Andrographis paniculata transcriptome provides molecular insights into tissue...
Abstract Background Kalmegh (Andrographis paniculata) has been widely exploited in traditional medicine for the treatment of infectious diseases and health disorders.... -
Systematic design of separation process for bioethanol production from corn s...
Abstract Separation process is very crucial in bioethanol production as it consumes the highest energy in the process. Unlike other works, this research systematically designed... -
Synthesis and biological activity of myricetin derivatives containing 1,3,4-t...
Abstract Background Myricetin and 1,3,4-thiadiazole derivatives were reported to exhibit favorable antiviral and antibacterial activities. Aiming to discover novel myricetin... -
Examining the role of unmeasured confounding in mediation analysis with genet...
Abstract Background In mediation analysis if unmeasured confounding is present, the estimates for the direct and mediated effects may be over or under estimated. Most methods... -
A genome-wide siRNA screen identifies a druggable host pathway essential for ...
Abstract Background The 2014–2016 Ebola virus (EBOV) outbreak in West Africa highlighted the need for improved therapeutic options against this virus. Approaches targeting host... -
Circulating heat shock protein 27 as a novel marker of subclinical atheroscle...
Abstract Background Heat shock protein 27 (HSP27) has been proposed as a vital protective factor in atherosclerosis. The objective of the present study was to evaluate the... -
TSS-EMOTE, a refined protocol for a more complete and less biased global mapp...
Abstract Background Bacteria rely on efficient gene regulatory mechanisms to switch between genetic programs when they are facing new environments. Although this regulation can... -
The Dictyostelium discoideum homologue of Twinkle, Twm1, is a mitochondrial D...
Abstract Background DNA replication requires contributions from various proteins, such as DNA helicases; in mitochondria Twinkle is important for maintaining and replicating... -
Mass spectrometry-based identification and whole-genome characterisation of t...
Abstract Background The pteropine orthoreovirus (PRV) was isolated from monkey (Macaca fascicularis) faecal samples collected from human-inhabited areas in Lopburi Province,... -
Influence of wood species on toxicity of log-wood stove combustion aerosols: ...
Abstract Background Wood combustion emissions have been studied previously either by in vitro or in vivo models using collected particles, yet most studies have neglected... -
Characterisation of a niche-specific excretory–secretory peroxiredoxin from t...
Abstract Background The primary cause of parasitic gastroenteritis in small ruminants in temperate regions is the brown stomach worm, Teladorsagia circumcincta. Host immunity to... -
Meta-analysis of human gene expression in response to Mycobacterium tuberculo...
Abstract Background With the global emergence of multi-drug resistant strains of Mycobacterium tuberculosis, new strategies to treat tuberculosis are urgently needed such as... -
miR-124 attenuates Japanese encephalitis virus replication by targeting DNM2
Abstract Background Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that causes acute viral encephalitis in humans. Pigs are important amplifier hosts of JEV.... -
Stakeholder perspectives on the implementation of genetic carrier screening i...
Abstract Background In most countries, genetic carrier screening is neither offered, nor embedded in mainstream healthcare. Technological developments have triggered a two-fold... -
In-feed resin acids reduce matrix metalloproteinase activity in the ileal muc...
Abstract The chicken gut is constantly exposed to harmful molecules and microorganisms which endanger the integrity of the intestinal wall. Strengthening intestinal mucosal... -
Maternal influences on oral and faecal microbiota maturation in neonatal calv...
Abstract Background The dam is considered an important source of microbes for the calf; consequently, the development of calf microbiota may vary with farming system due to... -
Diverse effects of nitric oxide reductase NorV on Aeromonas hydrophila virule...
Abstract NorV has been known to be an anaerobic nitric oxide reductase associated with nitric oxide (NO) detoxification. Recently, we showed that the norV gene of Aeromonas... -
Antimicrobial activities and mechanism of action of Cymbopogon khasianus (Mun...
Abstract Background Due to concerns regarding the safety of the chemical control measures, the trend is shifting globally towards the use of natural compounds as antimicrobial...
