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Kinetic analysis of [18F] altanserin bolus injection in the canine brain usin...
Abstract Background Currently, [18F] altanserin is the most frequently used PET-radioligand for serotonin2A (5-HT2A) receptor imaging in the human brain but has never been... -
The ‘goodness-of-fit’ of fit models: creating a multidimensional survey for p...
Abstract Background Person-environment fit, which examines the individual’s perceptions of if, and in what way, he or she is compatible with aspects of the work context, offers... -
The JAK-STAT Pathway Is Critical in Ventilator-Induced Diaphragm Dysfunction
Abstract Mechanical ventilation (MV) is one of the lynchpins of modern intensive-care medicine and is life saving in many critically ill patients. Continuous ventilator support,... -
vvECMO can be avoided by a transpulmonary pressure guided open lung concept i...
vvECMO can be avoided by a transpulmonary pressure guided open lung concept in patients with severe ARDS -
Comparison of circulating lipid profiles between fasting humans and three ani...
Abstract Background Circulating lipid metabolites are associated with many physiological and biological processes in the body, and therefore could be used as biomarkers for... -
The effect of Baduanjin exercise on health-related physical fitness of colleg...
Abstract Background Low health-related physical fitness in college students is a risk factor for future development of cardiovascular diseases at later stages in life, but... -
Characterization of ten white matter tracts in a representative sample of Cub...
Abstract Background The diffusion tensor imaging technique (DTI) combined with tractography methods, has achieved the tridimensional reconstruction of white matter tracts in the... -
Nur77-mediated TRAF6 signalling protects against LPS-induced sepsis in mice
Abstract Background Nur77, a key member of the NR4A receptor subfamily, is involved in the regulation of inflammation and immunity. However, the in vivo regulatory roles of... -
A Nordic survey of CT doses in hybrid PET/CT and SPECT/CT examinations
Abstract Background Computed tomography (CT) scans are routinely performed in positron emission tomography (PET) and single photon emission computed tomography (SPECT)... -
Cogena, a novel tool for co-expressed gene-set enrichment analysis, applied t...
Abstract Background Drug repositioning, finding new indications for existing drugs, has gained much recent attention as a potentially efficient and economical strategy for... -
Compressing gene expression data using multiple latent space dimensionalities...
Abstract Background Unsupervised compression algorithms applied to gene expression data extract latent or hidden signals representing technical and biological sources of... -
Inhibition of RNA polymerase II allows controlled mobilisation of retrotransp...
Abstract Background Retrotransposons play a central role in plant evolution and could be a powerful endogenous source of genetic and epigenetic variability for crop breeding. To... -
In silico modeling of phosphorylation dependent and independent c-Myc degrada...
Abstract Background c-Myc plays an important role in cell proliferation, cell growth and in differentiation, making it a key regulator for carcinogenesis and pluripotency. Tight... -
Does CRP predict outcome in bipolar disorder in regular outpatient care?
Abstract Background The association between inflammation and the course of mood disorders is receiving increased attention. This study aims to investigate whether a sub-group of... -
Brain computerized tomography reading in suspected acute ischemic stroke pati...
Abstract Background Few systematic methods prioritize the image education in medical students (MS). We hope to develop a checklist of brain computerized tomography (CT) reading... -
Development and validation of a model for temporal lobe necrosis for nasophar...
Abstract Purpose To develop and validate a quantitative complication model of temporal lobe necrosis (TLN). To analyze the effect of clinical and dosimetric factors on TLN.... -
Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apopt...
Abstract Background A sustained inflammatory response following spinal cord injury (SCI) contributes to neuronal damage, inhibiting functional recovery. Macrophages, the major... -
Core Outcome Set-STAndardised Protocol Items: the COS-STAP Statement
Abstract Background Several hundred core outcome set (COS) projects have been systematically identified to date which, if adopted, ensure that researchers measure and report... -
Cryptic sequence features in the active postmortem transcriptome
Abstract Background Our previous study found that more than 500 transcripts significantly increased in abundance in the zebrafish and mouse several hours to days postmortem... -
Why hospital physicians attend work while ill? The spiralling effect of posit...
Abstract Background Recurrent reports from national and international studies show a persistent high prevalence of sickness presence among hospital physicians. Despite the...