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Activation of dopamine D1 receptor decreased NLRP3-mediated inflammation in i...
Abstract Background Inflammasomes are involved in diverse inflammatory diseases. Previous study reported that the neurotransmitter dopamine inhibited NLRP3 inflammasome... -
Venovenous extracorporeal membrane oxygenation devices-related colonisations ...
Abstract Background Nosocomial infections occurring during extracorporeal membrane oxygenation (ECMO) support have already been reported, but few studied infections directly... -
Elevated Kallikrein-binding protein in diabetes impairs wound healing through...
Abstract Background The accumulation of M1-polarized macrophages and excessive inflammation are important in the pathogenesis of diabetic foot ulcer (DFU). However, the... -
State-Aware Concurrency Throttling
Abstract: Reconfiguration of parallel applications has gained traction with the increasing emphasis on energy/performance trade-off. The ability to dynamically change the amount... -
A combination of SOFA score and biomarkers gives a better prediction of septi...
Abstract Background Sepsis is a syndrome characterized by a constellation of clinical manifestations and a significantly high mortality rate in the surgical intensive care unit... -
Additional file 2 of Tumor necrosis factor-alpha promotes survival in methotr...
Authors’ original file for figure 2 -
Involvement of MAPK signalling in radioadaptive response in BALB/c mice expos...
To investigate low dose ionizing radiation (LDIR)-induced adaptive response in lymphocytes of BALB/c mice and to elucidate related molecular mechanisms. Mice were exposed to a... -
Results of questionnaire on live plant health nematode collections
In the framework of the Euphresco project 2016-F-186 'Inventory of living collections of cyst and root knot nematodes in Europe and their maintenance techniques (Cyst and... -
Additional file 5: of Inflammatory interferon activates HIF-1α-mediated epith...
Figure S5. The IFN-α not only attenuated MX-induced apoptosis, but also promote PI3K- and MAPK-P38-dependent invasion activity.(A) IFN-α co-treatment reduced the MX-induced... -
Regulation of platelet-activating factor-induced interleukin-8 expression by ...
Abstract Background Platelet-activating factor (PAF) is a potent lipid mediator whose involvement in the onset and progression of atherosclerosis is mediated by, among others,... -
Additional figure 1:
Cell cycle distribution of SW1353 cultured in 2D. Representative histogram, showing the cell cycle phases of SW1353 cultured in 2D. G0/G1 phase is represented in blue, S phase... -
Additional file 1 of Acute and long-term effects of antibiotics commonly used...
Additional file 1. DNA yields from a single fecal pellet of adult C57BL/6NHsd (A) and C57BL/6J (B) mice (n = 12/source) before (pre), immediately after (post), and four weeks... -
Additional file 7 of Comprehensive mapping of the cell response to E. coli in...
Additional file 7. DEGs involved in the cytokine–cytokine receptor interaction pathway. DEGs from the cytokine–cytokine receptor interaction pathway found in the cells subjected... -
Dimethyl fumarate attenuates experimental autoimmune neuritis through the nuc...
Abstract Background Guillain–Barré syndrome (GBS) is an acute, post-infectious, immune-mediated, demyelinating disease of peripheral nerves and nerve roots. Dimethyl fumarate... -
Additional file 2: of Novel insights into neuroinflammation: bacterial lipopo...
Preliminary experiments with HBMEC. A dose dependent induction of ICAM-1 mRNA in HBMEC was revealed by qRT-PCR. LPS-evoked response peaked at 100 ng/ml (A), whereas TNF-α doses... -
A Surface-Induced Asymmetric Program Promotes Tissue Colonization by a Human ...
Raw data used for Fig. 4A of the article "A Surface-Induced Asymmetric Program Promotes Tissue Colonization by a Human Pathogen" published in Cell Host & Microbe.... -
Characteristics of included studies.
RCT: Randomised controlled trial. GS: Gilead Sciences. R: Roche. GSK: GlaxoSmithKline. NS: not stated. aCopies/mL converted to IU/mL by dividing by 5.bThe limit of detection of... -
Individual and stable autoantibody repertoires in healthy individuals
In the era towards precision medicine, we here present the individual specific autoantibody signatures of 193 healthy individuals. The self-reactive IgG signatures are stable...