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Exome sequencing in routine diagnostics: a generic test for 254 patients with...
Abstract Background Diagnosis of primary immunodeficiencies (PIDs) is complex and cumbersome yet important for the clinical management of the disease. Exome sequencing may... -
Functional characterization of BmOVOs in silkworm, Bombyx mori
Abstract Background In our previous study, we identified four isoforms of the Bmovo gene, Bmovo-1, Bmovo-2, Bmovo-3 and Bmovo-4 from the silkworm ovary and verified that ovarian... -
Additional file 2: Table S1. of Integrated analyses of zebrafish miRNA and mR...
Unfiltered enriched GO terms associated with over-expressed gene set. Table contains each GO category and p-value. (XLS 29Â kb) -
Comprehensive analysis of LDHAP5 pseudogene expression and potential pathogen...
Abstract Background We aimed to identify differentially expressed pseudogenes and explore their potential functions in four types of common gynecological malignancies (e.g.,... -
TNFAIP8 promotes AML chemoresistance by activating ERK signaling pathway thro...
Abstract Background Chemoresistance is emerging as a major barrier to successful treatment in acute myeloid leukemia (AML), and evasion of apoptosis is among the fundamental... -
Additional File 1:
Fig. S1. The prescribed CGA form. The prescribed form was completed with many findings from each ESAT professional within the initial 2 days. These information and data were... -
Genome-wide characterization of human L1 antisense promoter-driven transcripts
Abstract Background Long INterspersed Element-1 (LINE-1 or L1) is the only autonomously active, transposable element in the human genome. L1 sequences comprise approximately 17... -
ΗΙF1α, EGR1 and SP1 co-regulate the erythropoietin receptor expression under ...
Abstract Background Overexpression of erythropoietin (EPO) and EPO receptor (EPO-R) is associated with poor prognosis in non-small-cell lung carcinoma (NSCLC). Hypoxia, a potent... -
Additional file 7 of Enhanceosome transcription factors preferentially dimeri...
Comparison of human and mouse dimer selected genes. Fisherâ s exact test p-values for comparing human and mouse dimer selected genes for all pairs of cell types from human and... -
Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of pa...
Abstract Muscle atrophy with weakness is a core feature of amyotrophic lateral sclerosis (ALS) that has long been attributed to motor neuron loss alone. However, several studies... -
Additional file 1: Figure S1. of Anti-N-methyl-D-aspartate receptor encephali...
Chemokine and cytokine levels in CSF and peripheral blood. The Wilcoxon signed ranked test was used for pairwise analyses of the CSF and sera samples to detect differences... -
Identification of Matrix Metalloproteinase-12 as a Candidate Molecule for Pre...
Abstract Obesity is strongly associated with metabolic syndrome, a combination of risk factors that predisposes to development of the cardiometabolic diseases: atherosclerotic... -
dedup_wf_001--026cd6a918534c9a8ebe60fffd109199
Additional file 5: Figure S4. The effects of downregulation of TNFAIP8 in THP-1 and U937. a TNFAIP8 knockdown (shTNFAIP8) or nonsilencing scrambled control (shNC) THP1 and U937... -
Additional file 2: Table S1. of Integrated analyses of zebrafish miRNA and mR...
Unfiltered enriched GO terms associated with over-expressed gene set. Table contains each GO category and p-value. (XLS 29Â kb) -
Source Data
Synthetic mimics of chlorophyll, which is designed by replacing the Mg center of porphyrin unit with other metal atoms (Au, Cu, Co) on metal-organic frameworks, may maximize... -
Genomic analysis of the tryptome reveals molecular mechanisms of gland cell e...
Abstract Background Understanding the drivers of morphological diversity is a persistent challenge in evolutionary biology. Here, we investigate functional diversification of... -
Identification and validation of a Schistosoma japonicum U6 promoter
Abstract Background RNA polymerase III promoters have been widely used to express short hairpin-RNA (shRNA), microRNA (miRNA), and small guide RNA (sgRNA) in gene functional... -
Additional file 7: Table S16. of Comprehensive promoter level expression quan...
All identified sentinel cis eQTLs. List of possible causal variant cis eQTL based on location and lowest p value including CAGE-cluster and SNPs chromosomal positions; gene ID;... -
Additional file 1: of The associations between proprotein convertase subtilis...
Checklist S1 PRISMA Checklist. (DOC 54 kb) -
Additional file 2: Figure S2. of Preliminary study of the UL55 gene based on ...
Schematic illustration of the strategy used to construct infectious DEV CHv BAC clone, UL55 deletion mutant and it’s revertant. (a) Schematic presentation of the organization of...