-
Endovascular external carotid artery occlusion for brain selective targeting:...
Abstract Background The choice of an animal model for cerebrovascular research is often determined by the disease subtype to be studied (e.g. ischemic stroke, hemorrhage,... -
Dimethyl fumarate attenuates reactive microglia and long-term memory deficits...
Abstract Background Systemic inflammation is associated with increased cognitive decline and risk for Alzheimer’s disease. Microglia (MG) activated during systemic inflammation... -
Gout is not associated with the risk of fracture: a meta-analysis
Abstract Background Numerous quantitatively based studies measuring the association between gout and the risk of fractures remain inconclusive. In order to determine whether... -
Association between component-resolved diagnosis of house dust mite and effic...
Abstract Data regarding clinical relevance of house dust mite (HDM) components over allergen immunotherapy (AIT) for allergic rhinitis (AR) are lacking. 18 adult AR patients... -
Combination of Ranibizumab with macular laser for macular edema secondary to ...
Abstract Background It is not clear whether macular laser combined with anti-vascular endothelial growth factor (VEGF) can reduce the number of anti-VEGF injections in the... -
Probiotics in pregnancy: protocol of a double-blind randomized controlled pil...
Abstract Background Maternal prenatal depressive or anxiety symptoms are associated with adverse maternal and infant health outcomes. With prevalence rates of maternal prenatal... -
Identification of plasma microRNA expression changes in multiple system atrop...
Abstract MicroRNAs (miRNAs) are endogenous small (18–25 nt), single-stranded, non-coding RNAs that play key roles in post-transcriptional gene expression regulation. The... -
Possible beneficial association between renin-angiotensin-aldosterone-system ...
Abstract Background Although immunoglobulin A nephropathy (IgAN) is associated with an increased risk of renal allograft failure, evidences for its treatment, including... -
Driving pressure is not associated with mortality in mechanically ventilated ...
Abstract Background In patients with acute respiratory distress syndrome (ARDS), low tidal volume ventilation has been associated with reduced mortality. Driving pressure (tidal... -
Neuronal impairment following chronic Toxoplasma gondii infection is aggravat...
Abstract Background It has become increasingly evident that the immune and nervous systems are closely intertwined, relying on one another during regular homeostatic conditions.... -
Gout and sexual function: patient perspective of how gout affects personal re...
Abstract Background In absence of previous studies, we assessed how gout impacts relationship and intimacy with spouse/significant other. Methods We enrolled a convenience... -
The potassium channel KCa3.1 represents a valid pharmacological target for mi...
Abstract Background Recent studies described a critical role for microglia in Parkinson’s disease (PD), where these central nerve system resident immune cells participate in the... -
Changes in physical activity during transition to retirement: a cohort study
Abstract Background Retirement is a major life transition which may affect lifestyle. The aim of this study is to examine within-individual changes in physical activity during... -
Relationship between age and bronchodilator response at diagnosis in adult-on...
Abstract Background Possible variation in bronchodilator response (BDR) according to age at the diagnosis of adult-onset asthma is unknown. Our aim was to assess if BDR in FEV1... -
iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated d...
Abstract Background Previous research indicated that nitric oxide synthase (NOS) is the key molecule for S-nitrosylation of ryanodine receptor 1 (RyR1) in DMD model mice (mdx... -
Transcriptomic data from two primary cell models stimulating human monocytes ...
Abstract Background Biological interpretation of DNA microarray data may differ depending on underlying assumptions and statistical tests of bioinformatics tools used. We used... -
Transient receptor potential ankyrin 1 (TRPA1) is functionally expressed in p...
Abstract Background Transient receptor potential ankyrin 1 (TRPA1) is a membrane-associated cation channel, widely expressed in neuronal cells and involved in nociception and... -
Use of a decision aid did not decrease decisional conflict in patients with c...
Abstract Background Although a model for shared decision-making is important for patient-centered care, decisional conflict can emerge when patients participate in the... -
Copenhagen comorbidity in HIV infection (COCOMO) study: a study protocol for ...
Abstract Background Modern combination antiretroviral therapy (cART) has improved survival for people living with HIV (PLWHIV). Non-AIDS comorbidities have replaced... -
Do some anxiety disorders belong to the prodrome of bipolar disorder? A clini...
Abstract Background In clinical practice, some patients diagnosed with anxiety disorder (AD) may develop bipolar disorder (BD) many years later, and some cases of AD may be...
