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DNA methylation and obesity traits: An epigenome-wide association study. The ...
Obesity is associated with increased risk of several diseases and has become epidemic. Obesity is highly heritable but the genetic variants identified by genome-wide association... -
The literature on Triassic, Jurassic and earliest Cretaceous dinoflagellate c...
Since the publication of five literature compilations issued between 2012 and 2020, 63 further published contributions on Triassic, Jurassic and earliest Cretaceous (Berriasian)... -
Genetic testing in a gynaecological oncology care in developing countries—kno...
Abstract Background Genetic testing for an inherited susceptibility to cancer is an emerging technology in medical practice. Little information is currently available about... -
Cost of inappropriate antimicrobial use for upper respiratory infection in Japan
Abstract Background Antibiotics are often prescribed inappropriately to patients with upper respiratory infection (URI) in ambulatory care settings; however, the economic burden... -
Variability of Uncrossmatched Blood Use by Helicopter EMS Programs in the Uni...
Study Objective: Some helicopter emergency medical services (HEMS) maintain an independent supply of blood for use during transport, although practice is variable and not well... -
Pre-pubertal males practising Taekwondo exhibit favourable postural and neuro...
Abstract Background The postural and neuromuscular performances in healthy children taekwondo (TKD) practitioners in comparison with control children were examined. Methods... -
Ecological factors associated with suicide mortality among non-Hispanic whites
Abstract Background In this paper, we examine the ecological factors associated with death rates from suicide in the United States in 1999 and 2017, a period when suicide... -
Patterns of olfactory dysfunctions in patients with Parkinson disease
Abstract Background Olfactory dysfunction (OD) is a well-established nonmotor manifestations (NMM) of Parkinson disease (PD) which needs objective assessment for better... -
Causal effect of smoking on DNA methylation in peripheral blood: a twin and f...
Abstract Background Smoking has been reported to be associated with peripheral blood DNA methylation, but the causal aspects of the association have rarely been investigated. We... -
The Blessings of Multiple Causes
Causal inference from observational data is a vital problem, but it comes with strong assumptions. Most methods assume that we observe all confounders, variables that affect... -
Impact of radiographer immediate reporting of chest X-rays from general pract...
Abstract Background Diagnostic capacity and suboptimal logistics are consistently identified as barriers to timely diagnosis of cancer, especially lung cancer. Immediate chest... -
Infant regulatory function acts as a protective factor for later traits of au...
Abstract Background Reduced executive functions (EF) are commonly associated with developmental conditions (e.g., autism spectrum disorder, ASD; attention deficit/hyperactivity... -
Measuring inconsistency in research ethics committee review
Abstract Background The review of human participant research by Research Ethics Committees (RECs) or Institutional Review Boards (IRBs) is a complex multi-faceted process that... -
Readability of patient information and consent documents in rheumatological s...
Abstract Background Before participation in medical research an informed consent must be obtained. This study investigates whether the readability of patient information and... -
Pain is a common problem in patients with ILD
Abstract Background As it is less known about the prevalence and characteristics of pain in the patients with interstitial lung disease (ILD), this paper aims at determining the... -
Module and individual domain deletions of NRPS to produce plipastatin derivat...
Abstract Background Plipastatin, an antifungal lipopeptide, is synthesized by a non-ribosomal peptide synthetase (NRPS) in Bacillus subtilis. However, little information is... -
Quantitative analysis of a rare disease network’s international contact datab...
Abstract Background Castleman disease (CD) describes a group of rare and poorly understood lymphoproliferative disorders that include unicentric CD (UCD), Human Herpes Virus-8... -
Psychometric properties of the newly developed Physician Teaching Self-Effica...
Abstract Background High teaching quality and students’ corresponding learning progress are the most important indicators of teachers’ work performance. Theory and numerous... -
Bursicon-α subunit modulates dLGR2 activity in the adult <i>Drosophila</i> me...
Bursicon is the main regulator of post molting and post eclosion processes during arthropod development. The active Bursicon hormone is a heterodimer of Burs-α and Burs-... -
Recommendations from the European Working Group for Value Assessment and Fund...
Abstract Rare diseases are an important public health issue with high unmet need. The introduction of the EU Regulation on orphan medicinal products (OMP) has been successful in...
