446 items found

Organisations: RISIS2OpenData Groups: Datacite Tags: Biotechnology Cell Biology Computational Biology Genetics

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  • dataset

    Regulatory role of rpL3 in cell response to nucleolar stress induced by Act D...

    Many chemotherapeutic drugs cause nucleolar stress and p53-independent pathways mediating the nucleolar stress response are emerging. Here, we demonstrate that ribosomal stress...
  • dataset

    Additional file 1: Table S1. of A retrospective cohort study of factors relat...

    Univariate Pearson correlation coefficients between independent variables and birth weight, birth length, and ponderal index. Table S2. Univariate Pearson correlation...
  • dataset

    Therapeutic potential of mesenchymal stem cells and their exosomes in severe ...

    Abstract The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19) and the ensuing...
  • dataset

    Additional file 1: of Continuous hemofiltration improves the prognosis of bac...

    No. of patients, age, BMI, length of PICU stay, Body temperature, PRISM III, group (“0” for conventional group, “1” for CRRT group), prognosis (“0” for survivor, “1” for...
  • dataset

    Independent modulation of individual genomic component transcription and a ci...

    Abstract Background The genome of Banana bunchy top virus (BBTV) consists of at least six circular, single-stranded DNA components of ~ 1 kb in length. Some BBTV isolates may...
  • dataset

    Additional file 2: of Adverse pregnancy outcomes in rural Uganda (1996–2013):...

    Factors associated with abortion, among 2557 women aged 15–49 years reporting a pregnancy in the past 12 months (1996–2013). (DOCX 17 kb)
  • dataset

    Low birth weight leads to obesity, diabetes and increased leptin levels in ad...

    Abstract Background Low birth weight is associated with increased rates of obesity, insulin resistance and type 2 diabetes, but the precise mechanisms for this association...
  • dataset

    MOESM2 of Paclitaxel-activated astrocytes produce mechanical allodynia in mic...

    Additional file 2: Figure S2. Cytokine array indicates potential regulation of chemokines in astrocytes after paclitaxel exposure. A, Illustration of the cytokine array with 40...
  • dataset

    Activation of <i>PPARγ2</i> by PPARγ1 through a functional PPRE in transdiffe...

    PPARγ and Wnt signaling are central positive and negative regulators of adipogenesis, respectively. Here we identified that, eicosapentaenoic acid (EPA) could effectively induce...
  • dataset

    Dairy intake revisited – associations between dairy intake and lifestyle rela...

    Abstract Background The association between milk and dairy intake and the incidence of cardiometabolic diseases, cancer and mortality has been evaluated in many studies, but...
  • dataset

    Emerging MET tyrosine kinase inhibitors for the treatment of non-small cell l...

    aberrations, including MET exon 14 skipping mutation and amplification, are present in ~5% of non-small cell lung cancer (NSCLC) cases, and these levels are comparable to the...
  • dataset

    Frequent hypermethylation of orphan CpG islands with enhancer activity in cancer

    Abstract Background CpG islands (CGIs) are interspersed DNA sequences that have unusually high CpG ratios and GC contents. CGIs are typically located in the promoter of...
  • dataset

    A novel transcription factor specifically regulates GH11 xylanase genes in Tr...

    Abstract Background The filamentous fungus Trichoderma reesei is widely utilized in industry for cellulase production, but its xylanase activity must be improved to enhance the...
  • dataset

    Additional file 1: of Oct4 regulates DNA methyltransferase 1 transcription by...

    Figure S1. Promoter analysis of mouse Dnmt1 in NIH3T3 and CCE cells using the luciferase assay. A – The promoter activity of mouse Dnmt1 in NIH3T3 and CCE cells. Oct4-pcDNA3.1...
  • dataset

    Comparison of monocyte human leukocyte antigen-DR expression and stimulated t...

    Abstract Background Identifying patients in the immunosuppressive phase of sepsis is essential for development of immunomodulatory therapies. Little data exists comparing the...
  • dataset

    Regulatory role of microRNA in mesenteric lymph nodes after Salmonella Typhim...

    Abstract Salmonellosis is a gastrointestinal disease caused by non-typhoidal Salmonella serovars such as Salmonella Typhimurium. This pathology is a zoonosis, and food animals...
  • dataset

    Additional file 10 of Analysis of genetic networks regulating refractive eye ...

    Table S23. List of mouse genes displaying significant association with refractive error in both UK Biobank and CREAM cohorts, and whose expression correlates with baseline...
  • dataset

    Additional file 1: of Connect MDS/AML: design of the myelodysplastic syndrome...

    Ethics Committees/Review Boards Which Approved the Connect MDS/AML Study. A list of all Institutional Review Boards that have approved the Connect MDS/AML Disease Registry...
  • dataset

    Additional file 17 of Unraveling the molecular interactions involved in phase...

    Additional file 17: Supplementary Table S5. Related to Fig. 6. Raw data.
  • dataset

    Trends in primeval β-hCG level increment after fresh and frozen-thawed IVF em...

    Mid-trimester beta-human chorionic gonadotropin (BHCG) levels are considerably higher in pregnancies resulting from frozen embryo transfer (FET) compared with fresh (FRET),...