49 items found

Organisations: RISIS2OpenData Tags: Biotechnology Cell Biology Medicine mesheuropmc.eye diseases Groups: Datacite Types: other

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    Oxidative stress and premature senescence in corneal endothelium following pe...

    Abstract Background The purpose of this study was to address the question of how the premature senescence process may affect corneal endothelium after penetrating keratoplasty,...
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    Long-term Safety and Efficacy of Human-Induced Pluripotent Stem Cell (iPS) Gr...

    Abstract The U.S. Food and Drug Administration recently approved phase I/II clinical trials for embryonic stem (ES) cell-based retinal pigmented epithelium (RPE)...
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    Combination of Ranibizumab with macular laser for macular edema secondary to ...

    Abstract Background It is not clear whether macular laser combined with anti-vascular endothelial growth factor (VEGF) can reduce the number of anti-VEGF injections in the...
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    Impact of an influenza information pamphlet on vaccination uptake among Polis...

    Abstract Background In Edinburgh, Scotland, lower influenza vaccine uptake has been observed in primary school children in the Polish community. Methods To address this...
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    High-resolution dual-modality photoacoustic ocular imaging

    We have developed a prototype ocular imaging system that integrates optical-resolution photoacoustic microscopy and high-frequency ultrasound imaging. The system can perform...
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    En-face optical coherence tomography - a novel application of non-invasive im...

    Optical Coherence Tomography (OCT) is an optical interferometric technique developed mainly for in vivo imaging of the eye and biological tissues. In this paper, we demonstrate...
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    Development of a core outcome set for amblyopia, strabismus and ocular motili...

    Abstract Background Core Outcome Sets (COS) are defined as the minimum sets of outcomes that should be measured and reported in all randomised controlled trials to facilitate...
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    The neuroregenerative effects of topical decorin on the injured mouse cornea

    Abstract Background The cornea is innervated with a rich supply of sensory nerves that play important roles in ocular surface health. Any injury or pathology of the corneal...
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    Temporal multiplexing with adaptive optics for simultaneous vision

    We present and test a methodology for generating simultaneous vision with a deformable mirror that changed shape at 50 Hz between two vergences: 0 D (far vision) and −2.5 D...
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    Anti-fibrotic, anti-VEGF or radiotherapy treatments as adjuvants for pterygiu...

    Abstract Background Anti-fibrotic, anti-VEGF (vascular endothelial growth factor) medications, or radiotherapy, as adjuvant for pterygium surgical procedure, has been suggested...
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    Polarization-sensitive swept-source optical coherence tomography with continu...

    We present fiber-based polarization-sensitive swept-source optical coherence tomography (SS-OCT) based on continuous source polarization modulation. The light source is a...
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    Noninvasive multimodal imaging in diagnosing polypoidal choroidal vasculopathy

    Abstract Purpose To investigate the diagnostic accuracy of noninvasive multimodal imaging methods in diagnosing polypoidal choroidal vasculopathy (PCV) and distinguishing PCV...
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    Dynamic OCT measurement of corneal deformation by an air puff in normal and c...

    A new technique is presented for the non-invasive imaging of the dynamic response of the cornea to an air puff inducing a deformation. A spectral OCT instrument combined with an...
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    3D nondestructive testing system with an affordable multiple reference optica...

    Optical coherence tomography (OCT) is emerging as a powerful noncontact imaging technique, allowing high-quality cross-sectional imaging of scattering specimens...
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    Dermascope guided multiple reference optical coherence tomography

    In this paper, we report the feasibility of integrating a novel low cost optical coherence tomography (OCT) system with a dermascope for point-of-care applications. The proposed...
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    Minimal internal limiting membrane peeling with ILM flap technique for idiopa...

    Abstract Background Internal limiting membrane (ILM) peeling increases the idiopathic macular hole (IMH) closure rate but causes the inner retina dimplings. This study is to...
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    Fiber-based polarization-sensitive OCT for birefringence imaging of the anter...

    We demonstrate a prototype system of polarization-sensitive optical coherence tomography (PS-OCT) designed for clinical studies of the anterior eye segment imaging. The system...
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    Clinical outcomes of switching to aflibercept using a pro re nata treatment r...

    Abstract Background To assess the effect of switching patients previously incompletely treated with ranibizumab (RBZ) to aflibercept (AFL) using a pro re nata (PRN) treatment...
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    Association between Previous Cataract Surgery and Age-Related Macular Degener...

    Purpose: To assess the association between age-related macular degeneration (AMD) and previous cataract surgery.Methods: We studied 17,987 randomly selected participants from...
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    Noninvasive chorioretinal imaging in living rabbits using integrated photoaco...

    Most reported photoacoustic ocular imaging work to date uses small animals, such as mice and rats, the eyeball sizes of which are less than one-third of those of humans, posing...