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Omalizumab in patients with severe asthma and persistent sputum eosinophilia
Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who... -
Pleural effusion from intrathoracic migration of a ventriculo-peritoneal shun...
Abstract Background Pleural effusion is a rare complication of ventriculo-peritoneal (VP) cerebrospinal fluid (CSF) shunting and its diagnosis is difficult in patients with... -
Comparative analyses of the in vivo induction and transmission of α-synuclein...
Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central... -
Measuring inconsistency in research ethics committee review
Abstract Background The review of human participant research by Research Ethics Committees (RECs) or Institutional Review Boards (IRBs) is a complex multi-faceted process that... -
Factors influencing decision regret regarding placement of a PEG among substi...
Abstract Background A tube feeding decision aid designed at the Ottawa Health Research Institute was specifically created for substitute decision-makers who must decide whether... -
Computed tomography-derived area and density of pectoralis muscle associated ...
Abstract Background Muscle wasting is associated with prognosis in patients with chronic obstructive pulmonary disease (COPD). The cross-sectional area of skeletal muscles on... -
High-intensity exercise to promote accelerated improvements in cardiorespirat...
Abstract Background African Americans have a disproportionate prevalence and incidence of type 2 diabetes compared with Caucasians. Recent evidence indicates that low... -
Contacting out-of-hours primary care or emergency medical services for time-c...
Abstract Background Out-of-hours (OOH) healthcare services in Western countries are often differentiated into out-of-hours primary healthcare services (OOH-PC) and emergency... -
Micronutrient-rich dietary intake is associated with a reduction in the effec...
Abstract Background Informal recycling of electronic waste (e-waste) releases particulate matter (PM) into the ambient air. Human exposure to PM has been reported to induce... -
Incidence of idiopathic cardiomyopathy in patients with type 2 diabetes in Ta...
Abstract Background The epidemiology of diabetes and idiopathic cardiomyopathy have limited data. We investigated the overall and the age-, sex-, and urbanization-specific... -
Prevalence and profile of adverse drug reactions in high-risk pregnancy: a co...
Abstract Background Commonly used drugs in pregnant women include antihypertensives, hypoglycemic agents, analgesics, antimicrobials, antiemetics and antispasmodics but the use... -
The association between socioeconomic status and visual impairments among pri...
Abstract Background Glaucoma is one of the most leading causes of permanent visual impairments in Korea, and social expenses spent for the glaucoma are increasing. This study is... -
Prenatal smoking exposure and neuropsychiatric comorbidity of ADHD: a finnish...
Abstract Background Prenatal smoking exposure has been associated with attention-deficit/hyperactivity disorder (ADHD). ADHD is commonly associated with a wide spectrum of... -
TBCRC 002: a phase II, randomized, open-label trial of preoperative letrozole...
Abstract Background In preclinical studies, the expression of vascular endothelial growth factor (VEGF) in hormone receptor-positive breast cancer is associated with... -
Income differences in screening, incidence, postoperative complications, and ...
Abstract Background The incidence of thyroid cancer (TC) has increased rapidly over the past few decades in Korea. This study investigated whether the TC epidemic has been... -
Distinct immune responses of juvenile and adult oysters (Crassostrea gigas) t...
Abstract Since 2008, massive mortality events of Pacific oysters (Crassostrea gigas) have been reported worldwide and these disease events are often associated with Ostreid... -
Identification of metabolic syndrome using phenotypes consisting of triglycer...
Abstract Background The metabolic syndrome (MetS) has shown strong associations with the hypertriglyceridemic waist (HW) phenotype. The best anthropometric indicator of MetS... -
Knowledge of peri-menarcheal changes and a comparative analysis of the age at...
Abstract Background Menarche is an expected event that occurs during the development of every normal young girl. We designed this study to evaluate the knowledge of young school... -
Clinical burden of illness in patients with phenylketonuria (PKU) and associa...
Abstract Background Phenylketonuria (PKU) is an inherited deficiency in the enzyme phenylalanine hydroxylase (PAH), which, when poorly-managed, is associated with clinical... -
Electrical interferential current stimulation versus electrical acupuncture i...
Abstract Background Hemiplegic Shoulder Pain (HSP) is among common complications occurring after stroke leading to disability. This study was conducted to compare the effects of...
