-
Examining the role of unmeasured confounding in mediation analysis with genet...
Abstract Background In mediation analysis if unmeasured confounding is present, the estimates for the direct and mediated effects may be over or under estimated. Most methods... -
Multiphoton in vivo imaging with a femtosecond semiconductor disk laser
We use an ultrafast diode-pumped semiconductor disk laser (SDL) to demonstrate several applications in multiphoton microscopy. The ultrafast SDL is based on an optically pumped... -
Effect of dose and dose rate on temporal γ-H2AX kinetics in mouse blood and s...
Abstract Background Cesium-137 (137Cs) is one of the major and most clinically relevant radionuclides of concern in a radiological dispersal device, “dirty bomb” scenario as... -
A novel method for the quantification of fatty infiltration in skeletal muscle
Abstract Background Fatty infiltration of the skeletal muscle is a common but poorly understood feature of many myopathies. It is best described in human muscle, where... -
Noninvasive label-free imaging of microhemodynamics by optical-resolution pho...
In vivo microcirculatory imaging facilitates the fundamental understanding of many major diseases. However, existing techniques generally require invasive procedures or... -
Effect of withholding early parenteral nutrition in PICU on ketogenesis as po...
Abstract Background In critically ill children, omitting early use of parenteral nutrition (late-PN versus early-PN) reduced infections, accelerated weaning from mechanical... -
Computed tomography derived bone density measurement in the diabetic foot
Abstract Background The accurate and reliable measurement of foot bone density is challenging and there is currently no gold standard technique. Such measurement is particularly... -
Dynamic OCT measurement of corneal deformation by an air puff in normal and c...
A new technique is presented for the non-invasive imaging of the dynamic response of the cornea to an air puff inducing a deformation. A spectral OCT instrument combined with an... -
Air pollution-induced placental epigenetic alterations in early life: a candi...
Particulate matter (PM) exposure during in utero life may entail adverse health outcomes in later-life. Air pollution's adverse effects are known to alter gene expression... -
Structurally isolated photoactuation of graphene-mixed temperature-responsive...
Abstract This paper presents fabrication and actuation methods for a soft microrobot with a hybrid structure composed of soft microactuators and a rigid supporting body. This... -
CYP1A1 methylation mediates the effect of smoking and occupational polycyclic...
Abstract Background Multiple factors, including co-exposure between lifestyle and environmental risks, are important in susceptibility to oxidative DNA damage. However, the... -
A CLCA regulatory protein present in the chemosensory cilia of olfactory sens...
Abstract Background CLCA is a family of metalloproteases that regulate Ca2+-activated Cl− fluxes in epithelial tissues. In HEK293 cells, CLCA1 promotes membrane expression of an... -
Proximal tibial trabecular bone mineral density is related to pain in patient...
Abstract Background Our objective was to examine the relationships between proximal tibial trabecular (epiphyseal and metaphyseal) bone mineral density (BMD) and osteoarthritis... -
Faster and less phototoxic 3D fluorescence microscopy using a versatile compr...
Three-dimensional fluorescence microscopy based on Nyquist sampling of focal planes faces harsh trade-offs between acquisition time, light exposure, and signal-to-noise. We... -
C-reactive protein mediates the association between leisure-time physical act...
Abstract Background Although previous studies have reported the benefits of physical activity (PA) to lung function in middle-aged and older adults, the biological mechanisms... -
The association between occupational loading and spine degeneration on imagin...
Abstract Background There are inconsistencies in findings regarding the relationship of occupational loading with spinal degeneration or structural damage. Thus, a systematic... -
Self-illuminating quantum dots for non-invasive bioluminescence imaging of ma...
Abstract Background The fertility performance of animals is still a mystery and the full comprehension of mammalian gametes maturation and early embryonic development remains to... -
Advancing the pathologic phenotype of giant axonal neuropathy: early involvem...
Abstract Giant axonal neuropathy (GAN; ORPHA: 643; OMIM# 256850) is a rare, hereditary, pediatric neurodegenerative disorder associated with intracellular accumulations of... -
Upregulating MicroRNA-410 or Downregulating Wnt-11 Increases Osteoblasts and ...
Abstract Background Little is known regarding the functional role of microRNA-410 (miR-410) in osteonecrosis of the femoral head (ONFH); hence, the aim of the present study was... -
Effects of capillary refill time-vs. lactate-targeted fluid resuscitation on ...
Abstract Background Persistent hyperlactatemia has been considered as a signal of tissue hypoperfusion in septic shock patients, but multiple non-hypoperfusion-related...
