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MTMR2 promotes invasion and metastasis of gastric cancer via inactivating IFN...
Abstract Background The aberrant expression of myotubularin-related protein 2 (MTMR2) has been found in some cancers, but little is known about the roles and clinical relevance.... -
Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in...
Abstract Background Three-dimensional (3D) floating culture clumps of mesenchymal stem cell (MSC)/extracellular matrix (ECM) complexes (C-MSCs) consist of cells and... -
Successful implementation of an enhanced recovery after surgery (ERAS) protoc...
Abstract Background Infratentorial craniotomy patients have a high incidence of postoperative nausea and vomiting (PONV). Enhanced Recovery After Surgery (ERAS) protocols have... -
The Reproductive Agency Scale (RAS-17): development and validation in a cross...
Abstract Background Sustainable Development Goal (SDG) 5 prioritizes women’s empowerment and gender equality, alone and as drivers of other SDGs. Efforts to validate universal... -
Survival after heart transplantation for non-metastatic primary cardiac sarcoma
Abstract Background Heart transplantation is an uncommon treatment for unresectable and non-metastatic primary cardiac sarcomas, and the role of it is unclear. This study aims... -
Exosomes from embryonic mesenchymal stem cells alleviate osteoarthritis throu...
Abstract Background Mesenchymal stem cell therapy for osteoarthritis (OA) has been widely investigated, but the mechanisms are still unclear. Exosomes that serve as carriers of... -
The Axin2-snail axis promotes bone invasion by activating cancer-associated f...
Abstract Background In bone-invasive oral squamous cell carcinoma (OSCC), cancer-associated fibroblasts (CAFs) infiltrate into bony tissue ahead of OSCC cells. In the present... -
Epidural adipose tissue-derived mesenchymal stem cell activation induced by l...
Abstract Background Spinal metastasis is a major challenge in patients with advanced lung cancer, but the mechanisms in the organotropism of metastasis are still unclear.... -
Heat shock pretreatment improves mesenchymal stem cell viability by heat shoc...
Abstract Background Bone marrow mesenchymal stem cells (BMSCs) can partially repair chemotherapy-induced ovarian damage. However, low survival rate after transplantation hampers... -
Bone marrow mesenchymal stromal cells attenuate silica-induced pulmonary fibr...
Abstract Background Pulmonary fibrosis induced by silica dust is an irreversible, chronic, and fibroproliferative lung disease with no effective treatment at present. Previous... -
The imbalance in the complement system and its possible physiological mechani...
Abstract Background The clinical and experimental evidences for complement-cancer relationships are solid, whereas an epidemiological study reporting the imbalance of complement... -
Duodenal major papilla morphology can affect biliary cannulation and complica...
Abstract Background We investigated whether duodenal major papilla morphology could be a risk factor for failure of selective biliary cannulation (SBC) and post endoscopic... -
Epithelial and interstitial Notch1 activity contributes to the myofibroblasti...
Abstract Background Notch1 signalling is a stem-cell-related pathway that is essential for embryonic development, tissue regeneration and organogenesis. However, the role of... -
Dipeptidyl peptidase-4 is highly expressed in bronchial epithelial cells of u...
Abstract Background Type 2 helper T-cell cytokines including IL-13 play a central role in the pathogenesis of bronchial asthma (BA). During the course of our research, our... -
Dexmedetomidine expands monocytic myeloid-derived suppressor cells and promot...
Abstract Background Dexmedetomidine (DEX) has been reported to promote tumour metastases. However the underlying mechanisms remain unclear. The purpose of this study was to... -
Effect of maternal sleep, physical activity and screen time during pregnancy ...
Abstract Background Early life exposure in the uterus had a long-term effect on children’s health. As the prevalence of allergies is increasing with a remarkable sex difference,... -
Connexin32 plays a crucial role in ROS-mediated endoplasmic reticulum stress ...
Abstract Background Ischemia–reperfusion (I/R)-induced acute kidney injury (AKI) not only prolongs the length of hospital stay, but also seriously affects the patient’s survival... -
Patient Blood Management improves outcome in oncologic surgery
Abstract Background Patient Blood Management (PBM) is a systematic quality improving clinical model to reduce anemia and avoid transfusions in all kinds of clinical settings.... -
Multi-organ protection of ulinastatin in traumatic cardiac arrest model
Abstract Background Post-cardiac arrest syndrome, which has no specific curative treatment, contributes to the high mortality rate of victims who suffer traumatic cardiac arrest... -
The cullin4A is up-regulated in chronic obstructive pulmonary disease patient...
Abstract Background Chronic obstructive pulmonary disease (COPD) is a common respiratory disease with high morbidity and mortality. The most important pathophysiological change...
