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Clinical baseline and prognostic difference of platelet lymphocyte ratio (PLR...
Abstract Background Right-sided colon cancer (RCC) and left-sided colon cancer (LCC) differ with respect to their biology and genomic patterns, but inflammatory index variation... -
Mutational spectrum of acquired resistance to reversible versus irreversible ...
Abstract Background Over the past years, EGFR tyrosine kinase inhibitors (TKI) revolutionized treatment response. 1st-generation (reversible) EGFR TKI and later the 2nd... -
Ultrahigh speed Spectral / Fourier domain OCT ophthalmic imaging at 70,000 to...
We demonstrate ultrahigh speed spectral/Fourier domain optical coherence tomography (OCT) using an ultrahigh speed CMOS line scan camera at rates of 70,000–312,500 axial scans... -
High-speed terahertz reflection three-dimensional imaging using beam steering
High-speed terahertz (THz) reflection three-dimensional (3D) imaging is demonstrated using electronically-controlled optical sampling (ECOPS) and beam steering. ECOPS... -
Mesenchymal stem cell-derived exosomes improve motor function and attenuate n...
Abstract Background Machado-Joseph disease is the most common autosomal dominant hereditary ataxia worldwide without effective treatment. Mesenchymal stem cells (MSCs) could... -
Treatment outcomes of drug-resistant tuberculosis in the Netherlands, 2005–2015
Abstract Background Since in low incidence TB countries population migration and complex treatment of drug-resistant tuberculosis (DR-TB) patients are major issues, we aimed to... -
Translation and validation of two disease-specific patient-reported outcome m...
Abstract Background The Bladder Cancer Index (BCI) and Functional Assessment of Cancer Therapy-Bladder-Cystectomy (FACT-Bl-Cys) were developed to measure disease-specific... -
GMP-grade neural progenitor derivation and differentiation from clinical-grad...
Abstract Background A major challenge for the clinical use of human pluripotent stem cells is the development of safe, robust and controlled differentiation protocols.... -
The repeatability of superficial retinal vessel density measurements in eyes ...
Abstract Background To investigate the repeatability of superficial retinal vessel density measurements in healthy eyes with long axial length (AL) using optical coherence... -
Frequent hypermethylation of orphan CpG islands with enhancer activity in cancer
Abstract Background CpG islands (CGIs) are interspersed DNA sequences that have unusually high CpG ratios and GC contents. CGIs are typically located in the promoter of...
