-
Prototype foamy virus elicits complete autophagy involving the ER stress-rela...
Abstract Background Prototype foamy virus (PFV) is a member of the Spumaretrovirinae subfamily of retroviruses, which maintains lifelong latent infection while being... -
Novel mutation in the CHST6 gene causes macular corneal dystrophy in a black ...
Abstract Background Macular corneal dystrophy (MCD) is a rare autosomal recessive disorder that is characterized by progressive corneal opacity that starts in early childhood... -
Boron-deficiency-responsive microRNAs and their targets in Citrus sinensis le...
Abstract Background MicroRNAs play important roles in the adaptive responses of plants to nutrient deficiencies. Most research, however, has focused on nitrogen (N), phosphorus... -
Induction of PR-10 genes and metabolites in strawberry plants in response to ...
Abstract Background The soil-borne vascular pathogen Verticillium dahliae causes severe wilt symptoms in a wide range of plants including strawberry (Fragaria × ananassa). To... -
CRISPR/dCas9-mediated transcriptional improvement of the biosynthetic gene cl...
Abstract Background The CRISPR/dCas9 system is a powerful tool to activate the transcription of target genes in eukaryotic or prokaryotic cells, but lacks assays in complex... -
HN1 contributes to migration, invasion, and tumorigenesis of breast cancer by...
Abstract Background Hematological and neurological expressed 1 (HN1) is upregulated in many tumors, but the role of HN1 in breast cancer progression and its regulatory mechanism... -
Comparative analyses of the in vivo induction and transmission of α-synuclein...
Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central... -
Molecular characterization of flavanone 3-hydroxylase gene and flavonoid accu...
Abstract Background Among secondary metabolites, flavonoids are particularly crucial for plant growth, development, and reproduction, as well as beneficial for maintenance of... -
Saliva exosomes-derived UBE2O mRNA promotes angiogenesis in cutaneous wounds ...
Abstract Background Enhancing angiogenesis is critical for accelerating wound healing. Application of different types of exosomes (Exos) to promote angiogenesis represents a... -
Rice WRKY11 Plays a Role in Pathogen Defense and Drought Tolerance
Abstract Background Plants are frequently subjected to abiotic and biotic stresses, and WRKY proteins play a pivotal role in the response to such stress. OsWRKY11 is induced by... -
Periostin involved in the activated hepatic stellate cells-induced progressio...
Abstract Background Incomplete thermal ablation may induce invasiveness of hepatocellular carcinoma (HCC). Here, we investigated whether activated hepatic stellate cells (HSCs)... -
Use of a special Brazilian red-light emitting railroad worm Luciferase in bio...
Abstract Background Luciferases, enzymes that catalyze bioluminescent reactions in different organisms, have been extensively used for bioanalytical purposes. The most well... -
Estrogen receptor β inhibits breast cancer cells migration and invasion throu...
Abstract Background Estrogen receptor β (ERβ) has been reported to play an anti-cancer role in breast cancer, but the regulatory mechanism by which ERβ exerts this effect is not... -
Management of Inflammatory Arthritis in pregnancy: a National Cross-Sectional...
Abstract Background With improved therapies and management, more women with inflammatory arthritides (IA) are considering pregnancy. Our objective was to survey rheumatologists... -
Creation of reference DNA barcode library and authentication of medicinal pla...
Abstract Background Ayurveda is a system of traditional medicine that originated in ancient India, and it is still in practice. Medicinal plants are the backbone of Ayurveda,... -
Activation of the EIF2AK4-EIF2A/eIF2α-ATF4 pathway triggers autophagy respons...
The intestinal mucosa of Crohn disease (CD) patients is abnormally colonized by adherent-invasive E. coli (AIEC). Upon AIEC infection, autophagy is induced in host cells to... -
A novel transcription factor specifically regulates GH11 xylanase genes in Tr...
Abstract Background The filamentous fungus Trichoderma reesei is widely utilized in industry for cellulase production, but its xylanase activity must be improved to enhance the... -
Changes in the volatiles, chemical components and antioxidant activities of C...
Chinese jasmine tea, a type of flower-scented tea, is produced by repeatedly mixing the base tea with the aromatic flowers of Jasminum sambac. The aim of this study was to... -
CIDR: Ultrafast and accurate clustering through imputation for single-cell RN...
Abstract Most existing dimensionality reduction and clustering packages for single-cell RNA-seq (scRNA-seq) data deal with dropouts by heavy modeling and computational... -
Genome-wide transcriptional adaptation to salt stress in Populus
Abstract Background Adaptation to abiotic stresses is crucial for the survival of perennial plants in a natural environment. However, very little is known about the underlying...
