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Continue, adjust, or stop antipsychotic medication: developing and user testi...
Abstract Background People with psychosis struggle with decisions about their use of antipsychotics. They often want to reduce the dose or stop, while facing uncertainty... -
The contrasting role of technology as both supportive and hindering in the ev...
Abstract Background It is well known that people with mild cognitive deficits face challenges when performing complex everyday activities, and that the use of technology has... -
MRI of trunk muscles and motor and respiratory function in patients with myot...
Abstract Background Myotonic Dystrophy 1 (DM1) causes progressive myopathy of extremity muscles. DM1 may also affect muscles of the trunk. The aim of this study was to... -
The association of birth weight and postnatal growth with energy intake and e...
Abstract Background Low and high birth weight and accelerated postnatal weight gain are associated with an increased risk of obesity. Perinatal effects on energy intake and... -
A pilot feasibility randomised controlled trial of an adjunct brief social ne...
Abstract Background Approximately 3% of people receiving opioid substitution therapy (OST) in the UK manage to achieve abstinence from prescribed and illicit drugs within three... -
Erythropoietin as an add-on treatment for cognitive side effects of electroco...
Abstract Background Electroconvulsive therapy (ECT) is the most effective treatment for severe depression, but its use is impeded by its cognitive side effects. Novel treatments... -
The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzhe...
Abstract Background Synaptic degeneration is a central pathogenic event in Alzheimer’s disease that occurs early during the course of disease and correlates with cognitive... -
A meta-analysis of depressive symptoms among Ethiopian prisoners and a narrat...
Abstract Background The burden of depression in prisoners is increasing and factors such as co-existence of medical illness, lack of social support and longer duration of... -
Helios + Regulatory T cell frequencies are correlated with control of viral r...
Abstract Background The acute phase of HIV infection is characterized by massive depletion of CD4 T cells, high viral plasma levels and pronounced systemic immune activation.... -
Survey indicated that core outcome set development is increasingly including ...
Abstract Background There are numerous challenges in including patients in a core outcome set (COS) study, these can vary depending on the patient group. This study describes... -
Transforming manufacturing to be ‘good for planet and people’, through enabli...
Abstract Background The United Nations’ Sustainable Development Goals remind us of the urgent need for every business to operate in ways that are good for planet and people.... -
Transcriptionally induced enhancers in the macrophage immune response to Myco...
Abstract Background Tuberculosis is a life-threatening infectious disease caused by Mycobacterium tuberculosis (M.tb). M.tb subverts host immune responses to build a favourable... -
Appendectomy, cholecystectomy and diagnostic laparoscopy conducted before pre...
Abstract Background Non-obstetric surgery conducted during pregnancy may increase the risk of adverse birth outcomes like small for gestational age, preterm birth, and... -
Factors associated with health service orientation and active product marketi...
Abstract Background Little is known about pharmacy owners’ commitment to public health and health policy goals in the strategic planning of their business. The aim of this... -
Defining the clinical pathway in cochrane diagnostic test accuracy reviews
Abstract Background The value of a medical test depends on the context in which it might be used. Ideally, questions, results and conclusions of a diagnostic test accuracy (DTA)... -
Sex as predictor for achieved health outcomes and received care in ischemic s...
Abstract Background Differences in stroke care and health outcomes between men and women are debated. The objective of this study was to explore the relationship between... -
Vasoresponsiveness in patients with heart failure (VASOR): protocol for a pro...
Abstract Background Vasoplegia is a severe complication which may occur after cardiac surgery, particularly in patients with heart failure. It is a result of activation of... -
At what times during infection is SARS-CoV-2 detectable and no longer detecta...
Abstract Background Tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral ribonucleic acid (RNA) using reverse transcription polymerase chain reaction... -
The architecture of national boundary regimes: mapping immigration and citize...
Abstract In this article, I introduce a typology that maps the regulation of two fundamental boundaries of modern nation-states regarding immigration: territorial boundaries and... -
Influence of new societal factors on neovascular age-related macular degenera...
Abstract Background To assess the impact of unstudied societal factors for neovascular age-related macular degeneration (nAMD) on functional outcomes after anti-VEGFs. Methods...
