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BK-UM in patients with recurrent ovarian cancer or peritoneal cancer: a first...
Abstract Background BK-UM (CRM197) is a mutant form of diphtheria toxin and a specific inhibitor of heparin-binding epidermal growth factor-like growth factor (HB-EGF). We... -
New insights on serodiagnosis of trichinellosis during window period: early d...
Abstract The clinical diagnosis of trichinellosis is difficult because its clinical manifestations are nonspecific. Detection of anti-Trichinella IgG by ELISA using T. spiralis... -
Comparison of DNA quantification methodology used in the DNA extraction proto...
Abstract Background UK Biobank is a large prospective cohort study in the UK established by the Medical Research Council (MRC) and the Wellcome Trust to enable approved... -
National policies for the promotion of physical activity and healthy nutritio...
Abstract Background Health policy papers disseminate recommendations and guidelines for the development and implementation of... -
Diabetic retinopathy is associated with diastolic dysfunction in type 2 diabe...
Abstract Background To investigate the association between diabetic retinopathy (DR) and myocardial dysfunction in patients with type 2 diabetes and dilated cardiomyopathy... -
Atherosclerotic and thrombotic genetic and environmental determinants in Egyp...
Abstract Background Coronary artery disease (CAD) is the leading cause of morbidity and mortality worldwide. Multiple genetic variants in combination with various environmental... -
Biomarker analysis of the NeoSphere study: pertuzumab, trastuzumab, and docet...
Abstract Background NeoSphere showed significantly higher pathologic complete response (pCR) with neoadjuvant pertuzumab, trastuzumab, and docetaxel compared with trastuzumab... -
Role of mesenchymal stem cells, their derived factors, and extracellular vesi...
Abstract Liver failure is a severe clinical syndrome with a poor prognosis. Mesenchymal stem cell (MSC) transplantation has emerged as a new intervention in treating liver... -
Characterization and pathogenesis of aerosolized eastern equine encephalitis ...
Abstract Background Licensed antiviral therapeutics and vaccines to protect against eastern equine encephalitis virus (EEEV) in humans currently do not exist. Animal models that... -
A case report of intravenous posaconazole in hepatic and renal impairment pat...
Abstract Background Invasive aspergillosis (IA) is a fatal infectious complication among immunocompromised patients. Aspergillus terreus, the fourth common species can be... -
Quorum sensing of Streptococcus mutans is activated by Aggregatibacter actino...
Abstract Background The oral cavity is inhabited by complex microbial communities forming biofilms that can cause caries and periodontitis. Cell-cell communication might play an... -
Proteomics informed by transcriptomics for characterising active transposable...
Abstract Background Aedes aegypti is a vector for the (re-)emerging human pathogens dengue, chikungunya, yellow fever and Zika viruses. Almost half of the Ae. aegypti genome is... -
Differential host gene responses from infection with neurovirulent and partia...
Abstract Background Venezuelan equine encephalitis virus (VEEV) is an alphavirus in the family Togaviridae. VEEV causes a bi-phasic illness in mice where primary replication in... -
The invasome of Salmonella Dublin as revealed by whole genome sequencing
Abstract Background Salmonella enterica serovar Dublin is a zoonotic infection that can be transmitted from cattle to humans through consumption of contaminated milk and milk... -
Point of sampling detection of Zika virus within a multiplexed kit capable of...
Abstract Background Zika, dengue, and chikungunya are three mosquito-borne viruses having overlapping transmission vectors. They cause diseases having similar symptoms in human... -
Characterization of two novel intronic OPA1 mutations resulting in aberrant p...
Abstract Background We report two novel splice region mutations in OPA1 in two unrelated families presenting with autosomal-dominant optic atrophy type 1 (ADOA1) (ADOA or Kjer... -
Identification of nucleoid associated proteins (NAPs) under oxidative stress ...
Abstract Background Bacterial nucleoid consists of genome DNA, RNA, and hundreds of nucleoid-associated proteins (NAPs). Escherichia coli nucleoid is compacted towards the... -
Acute cigarette smoke exposure activates apoptotic and inflammatory programs ...
Abstract Background Smoking and aberrant epithelial responses are risk factors for lung cancer as well as chronic obstructive pulmonary disease and idiopathic pulmonary... -
[6]-Gingerol, from Zingiber officinale, potentiates GLP-1 mediated glucose-st...
Abstract Background [6]-Gingerol, a major component of Zingiber officinale, was previously reported to ameliorate hyperglycemia in type 2 diabetic mice. Endocrine signaling is... -
Serum low-density lipoprotein and low-density lipoprotein expression level at...
Abstract Background Patients with small-cell lung cancer (SCLC) patients demonstrate varied survival outcomes. Previous studies have reported that lipoproteins are associated...
