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Economic evaluation of nivolumab combined with ipilimumab in the first-line t...
The objective of this study was to evaluate the cost-effectiveness of nivolumab in combination with ipilimumab (nivo + ipi) compared to current therapeutic alternatives in... -
Distinct binding and signaling activity of Acthar Gel compared to other melan...
To compare the binding and agonistic activity of Acthar® Gel and synthetic melanocortin receptor (MCR) agonists and examine how the activity of select agonists affects the in... -
dedup_wf_001--aad5de0a2207e226aec94d5ef408710b
A previous survey investigated postmenopausal vaginal atrophy in a sample of women across Latin America. To help implement a tailored approach to improve postmenopausal care and... -
Medication therapy strategies for the coronavirus disease 2019 (COVID-19): re...
The coronavirus disease 2019 (COVID-19) pandemic has spread globally since it outbroke in December 2019. The urgent pandemic presents an unprecedented challenge to develop and... -
Burden of disease and costs associated with type 2 diabetes in emerging and e...
To estimate the clinical and economic burden of type 2 diabetes (T2D) in established (EST) and emerging markets (EMG). Three systematic literature reviews were conducted in... -
Systematic literature review of the epidemiology and clinical burden of chron...
We conducted a systematic literature review (SLR) to determine the epidemiology and clinical burden of chronic rhinosinusitis with nasal polyps (CRSwNP) and to describe how the... -
Intravitreal aflibercept: its role in treatment of neovascular age-related ma...
Introduction: Age related macular degeneration (AMD) affects over 14 million people worldwide and is the commonest cause of visual loss in the over 65’s age group in the... -
Association of tenofovir disoproxil fumarate exposure with chronic kidney dis...
Tenofovir disoproxil fumarate (TDF)-based regimens have been associated with impaired kidney function and loss of bone mineral density among patients living with HIV (PLWH). We... -
dedup_wf_001--ec3619771e810a154c5d52d33605d6ab
OBJECTIVE To assess evidence on the safety and efficacy of ABVD (doxorubicin [Adriamycin®], bleomycin, vinblastine, and dacarbazine), BEACOPP (bleomycin, etoposide, doxorubicin,... -
dedup_wf_001--a35e03ea4a8f433445518894738e3a56
Emergency Departments (ED) are rapidly becoming an important location for initiation of buprenorphine (EDBUP) for the treatment of opioid use disorder (OUD). Previous... -
dedup_wf_001--b2aea697ee420d2a6a886a8155e8b204
The β-D-Mannuronic acid (M2000) as a novel immunosuppressive drug, patented (PCT/EP2017/067920), has shown positive effects in experimental model of multiple sclerosis (MS). In... -
Societal implications of medical insurance coverage for imatinib as first-lin...
Objectives: Imatinib (Glivec) and nilotinib (Tasigna) have been covered by critical disease insurance in Jiangsu province of China since 2013, which changed local treatment... -
Chronic use of statins and risk of post-endoscopic retrograde cholangiopancre...
There is limited evidence on the role of chronic statin therapy in the prevention of acute pancreatitis after ERCP. The aim of this meta-analysis was to evaluate the efficacy of... -
Predictors of insufficient recanalization and portal hypertensive complicatio...
In acute portal vein thrombosis (PVT), a six-month anticoagulation treatment achieves complete recanalization in only 35%–45% of patients, but the predictors of poor treatment... -
Healthcare resource utilization and costs associated with postpartum depressi...
Objective: To quantify the economic burden of postpartum depression (PPD) that accrues to commercially insured households in the year following childbirth. Methods:... -
The Cold War as an Aesthetic Phenomenon: An Afterthought on Boris Groys
The Cold War as an Aesthetic Phenomenon: An Afterthought on Boris Groys -
Renal sympathetic denervation lowers systemic vascular resistance in true tre...
Renal sympathetic denervation (RDN) is again gaining interest as recent well-designed trials have demonstrated reduced ambulatory blood pressure (BP) after RDN. However, the... -
Cost utility analysis of tisagenlecleucel vs salvage chemotherapy in the trea...
Background: Patients with relapsed or refractory diffuse large B-cell lymphoma (r/r DLBCL) have limited treatment options and poor prognoses. Tisagenlecleucel, a chimeric... -
Impact of immunogenicity on efficacy and tolerability of tumour necrosis fact...
SB4, SB2, and SB5 are biosimilars of etanercept (ETN), infliximab (INF), and adalimumab (ADA), respectively. This pooled analysis evaluated the immunogenicity of these... -
dedup_wf_001--85e1e77b61e09eda8306fe2d0c80bb68
To assess gout and asymptomatic hyperuricemia in Japan and review treatment conditions. This retrospective cross-sectional study analyzed the prevalence of hyperuricemia and...
