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Broad phenotypic spectrum and genotype-phenotype correlations in GMPPB-relate...
Background Dystroglycanopathy (α-DG) is a relatively common, clinically and genetically heterogeneous category of congenital forms of muscular dystrophy (CMD) and limb-girdle... -
Maternal eating disorders affect offspring cord blood DNA methylation: a pros...
Background Eating disorders (ED) are chronic psychiatric disorders, common amongst women of reproductive age. ED in pregnancy are associated with poor nutrition and abnormal... -
IgM response against amyloid-beta in aging: a potential peripheral protective...
Background The immune system plays a major role in the pathogenesis of age-related dementia, including Alzheimer’s disease (AD). An insight into age-associated changes in the... -
Co-trimoxazole versus azithromycin for the treatment of undifferentiated febr...
Background Undifferentiated febrile illness (UFI) includes typhoid and typhus fevers and generally designates fever without any localizing signs. UFI is a great therapeutic... -
Development and validation of a prognostic model for recurrent glioblastoma p...
Background Predictive markers and prognostic models are required in order to individualize treatment of recurrent glioblastoma (GBM) patients. Here, we sought to identify... -
A transdiagnostic sleep and circadian treatment to improve severe mental illn...
Background Severe mental illness (SMI) is common, chronic and difficult to treat. Sleep and circadian dysfunctions are prominent correlates of SMI, yet have been minimally... -
Veteran-centered barriers to VA mental healthcare services use.
Background Some veterans face multiple barriers to VA mental healthcare service use. However, there is limited understanding of how veterans’ experiences and meaning systems... -
Trends in alcohol use among young people according to the pattern of consumpt...
Aim To identify differences in Risky Consumption (RC) and Binge drinking (BD) trends in students who already followed these patterns of alcohol consumption on starting... -
"Somatosensory abnormalities in Chinese patients with painful temporomandibul...
Background The somatosensory phenotype of Chinese temporomandibular disorders (TMD) patients is not sufficiently studied with the use of contemporary techniques and guidelines.... -
Associations of mutually exclusive categories of physical activity and sedent...
Background Both physical activity and sedentary behaviour have been individually associated with health, however, the extent to which the combination of these behaviours... -
From erasure to opportunity: a qualitative study of the experiences of transg...
Background Some transgender men retain their uterus, get pregnant, and give birth. However, societal attitudes about gender have erected barriers to openly being pregnant and... -
Cilostazol induced migraine does not respond to sumatriptan in a double blind...
Background Cilostazol is an inhibitor of phosphodiesterase 3 and thus causes accumulation of cAMP. It induces migraine-like attacks in migraine patients. Whether the cilostazol... -
Combined cognitive and vocational interventions after mild to moderate trauma...
Background A considerable proportion of patients with mild to moderate traumatic brain injury (TBI) experience long-lasting somatic, cognitive, and emotional... -
Natalizumab treatment reduces L-selectin (CD62L) in CD4+ T cells
Background The purpose of this research was to validate the low expression of L-selectin (CD62L) in natalizumab (NTZ)-treated patients. CD62L is involved in rolling and... -
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Background In 2011, the UK physical activity guidelines were updated to include recommendations for muscle strengthening and balance & coordination (at least two sessions of... -
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Previously depressed individuals experience disturbances in affect. Affective disturbances may be related to visual mental imagery, given that imagery-based processing of... -
Haploidentical transplantation is associated with better overall survival whe...
Background Thiotepa-busulfan-fludarabine (TBF) is a widely used conditioning regimen in single umbilical cord blood transplantation (SUCBT). More recently, it was introduced in... -
Defining a core outcome set for adolescent and young adult patients with a sp...
Background and purpose - Routine outcome measurement has been shown to improve performance in several fields of healthcare. National spine surgery registries have been initiated... -
Possible sexually dimorphic role of miRNA and other sncRNA in ASD brain
Background Autism spectrum disorder (ASD) is sexually dimorphic in brain structure, genetics, and behaviors. In studies of brain tissue, the age of the population is clearly a... -
Diagnosing depression in primary care: a Rasch analysis of the major depressi...
Objective: This study aimed to assess the measurement properties of the Major Depression Inventory (MDI) in a clinical sample of primary care patients. Design: General...
