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Acute respiratory failure in immunocompromised patients: outcome and clinical...
Abstract Background The impact of neutropenia in critically ill immunocompromised patients admitted in a context of acute respiratory failure (ARF) remains uncertain. The... -
Combined interventions to reduce HIV incidence in KwaZulu-Natal: a modelling ...
Abstract Background Combined prevention interventions, including early antiretroviral therapy initiation, may substantially reduce HIV incidence in hyperendemic settings. Our... -
Untapped potential of multicenter studies: a review of cardiovascular risk pr...
Abstract Background Clinical prediction models are often constructed using multicenter databases. Such a data structure poses additional challenges for statistical analysis... -
Pharmacological pain relief and fear of childbirth in low risk women; seconda...
Abstract Background Fear of childbirth may reduce the womens’ pain tolerance during labour and may have impact on the mother-infant interaction. We aimed to assess (1) the... -
Omic personality: implications of stable transcript and methylation profiles ...
Abstract Background Personalized medicine is predicated on the notion that individual biochemical and genomic profiles are... -
A comparison of self-report and antiretroviral detection to inform estimates ...
Abstract Background Accurately identifying individuals who are on antiretroviral therapy (ART) is important to determine ART coverage and proportion on ART who are virally... -
Predictors of fibromyalgia: a population-based twin cohort study
Abstract Background Fibromyalgia (FM) is a pain syndrome, the mechanisms and predictors of which are still unclear. We have... -
Detection of suspicious interactions of spiking covariates in methylation data
Abstract Background In methylation analyses like epigenome-wide association studies, a high amount of biomarkers is tested for an association between the measured continuous... -
Triplet Matching for Estimating Causal Effects with Three Treatment Arms: A C...
Comparing outcomes across different levels of trauma centers is vital in evaluating regionalized trauma care. With observational data, it is critical to adjust for patient... -
Accounting for matching structure in post-matching analysis of observational ...
Matching design is commonly used in social science and health research with observational data, as it is robust to outcome model misspecification and has the intuitive... -
Potential impact of multiple interventions on HIV incidence in a hyperendemic...
Abstract Background Multiple prevention interventions, including early antiretroviral therapy initiation, may reduce HIV incidence in hyperendemic settings. Our aim was to... -
Digital breast tomosynthesis for breast cancer screening and diagnosis in wom...
Abstract Background This study aimed to systematically review and to meta-analyse the accuracy of digital breast tomosynthesis (DBT) versus digital mammography (DM) in women... -
dedup_wf_001--ca59bce699e749920fbf0d37bb04d13e
Advances in high-throughput genomic technologies coupled with large-scale studies including The Cancer Genome Atlas (TCGA) project have generated rich resources of diverse types... -
Meta-analysis of the impact of alpha-glucosidase inhibitors on incident diabe...
Abstract Background Alpha-glucosidase inhibitors (AGIs) have been shown to reduce incident type 2 diabetes but their impact on... -
Specific trophoblast transcripts transferred by extracellular vesicles affect...
Abstract Background Successful establishment of pregnancy hinges on appropriate communication between the embryo and the uterus... -
Prognostic DNA methylation markers for hormone receptor breast cancer: a syst...
Abstract Background In patients with hormone receptor-positive breast cancer, differentiating between patients with a low and a high risk of recurrence is an ongoing challenge.... -
Genetic polymorphisms associated with sleep-related phenotypes; relationships...
Abstract Background In recent years, several GWAS (genome wide association studies) of sleep-related traits have identified a number of SNPs (single nucleotides polymorphism)...
