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Specificity versus redundancy in the RAP2.4 transcription factor family of Ar...
Abstract Background The Arabidopsis ERFIb / RAP2.4 transcription factor family consists of eight members with highly conserved DNA binding domains. Selected members have been... -
Predictors of delayed culture conversion among Ugandan patients
Abstract Background Estimates of month-2 culture conversion, a proxy indicator of tuberculosis (TB) treatment efficacy in phase-2 trials can vary by culture-type and... -
Role of goblet cell protein CLCA1 in murine DSS colitis
Abstract Background The secreted goblet cell protein CLCA1 (chloride channel regulator, calcium-activated-1) is, in addition to its established role in epithelial chloride... -
A transcriptomic snapshot of early molecular communication between Pasteuria ...
© The Author(s). 2018 -
Campylobacter jejuni infection of conventionally colonized mice lacking nucle...
Abstract Background The nucleotide-binding oligomerisaton protein 2 (NOD2) constitutes a pivotal sensor of bacterial muramyl dipeptide and assures expression of distinct... -
Biallelic modification of IL2RG leads to severe combined immunodeficiency in ...
Background: Pigs with SCID can be a useful model in regenerative medicine, xenotransplantation, and cancer cell transplantation studies. Utilizing genome editing technologies... -
Negligible risk of inducing resistance in Mycobacterium tuberculosis with sin...
Abstract Post-exposure prophylaxis (PEP) for leprosy is administered as one single dose of rifampicin (SDR) to the contacts of newly diagnosed leprosy patients. SDR reduces the... -
ショウジョウバエ野外集団におけるコアプロモーター配列変異によって生じる発現量変化への自然選択
Abstract Background Understanding the evolutionary forces that influence variation in gene regulatory regions in natural populations is an important challenge for evolutionary... -
The functional divergence between SPA1 and SPA2 in Arabidopsis photomorphogen...
Abstract Background Plants have evolved complex mechanisms to adapt growth and development to the light environment. The COP1/SPA complex is a key repressor of...
