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Pharmacokinetics and safety of ixazomib plus lenalidomide–dexamethasone in As...
Abstract Background The oral proteasome inhibitor ixazomib is under phase 3 clinical investigation in multiple myeloma (MM) in combination with lenalidomide–dexamethasone. This... -
Analytical characteristics and comparative evaluation of Aptima HCV quant Dx ...
Abstract Background The Aptima HCV Quant Dx assay (Aptima assay) is a fully automated quantitative assay on the Panther® system. This assay is intended for confirmation of... -
Additional file 4: of Vitamin D intervention in preschoolers with viral-induc...
Unadjusted serum 25-hydroxy vitamin D values over 6 months. The unadjusted values for total serum 25-hydroxy vitamin D (25OHD) are presented, by group, over the 6-month study... -
Insights from the ganglionic acetylcholine receptor autoantibodies in patient...
Objective: It is not known whether autonomic neuropathy is a feature of Sjögren’s syndrome (SS) or whether it is related to circulating antiganglionic acetylcholine receptor... -
Model parameters.
aSpecified with reference to Cook [30] and Waage et al. [36] using distributions defined in Biosecurity Australia [31]; b Derived from Sapoukhina et al. [37]; c ABS [6], Note... -
Are the public getting the message about antimicrobial resistance?
Abstract Raising public awareness of the need to use antibiotics appropriately is a major focus of the UK Governmentâ s strategy to tackle antimicrobial resistance. To... -
Additional file 4: Figure S3. of Urinary chitinase 3-like protein 1 for early...
Distribution of urinary chitinase 3-like protein 1 (UCHI3L1) (a) and urinary neutrophil gelatinase-associated lipocalin (UNGAL) (b) at enrollment in the eight selected subgroups... -
Increased expression of dedicator-cytokinesis-10, caspase-2 and Synaptotagmin...
Abstract Background We aim to identify differentially expressed genes (DEGs) and its pathways associated with clinical activity of relapsing–remitting Multiple Sclerosis (RRMS).... -
Additional file 1: of Sociodemographic, clinical, and psychosocial factors as...
This is a cleaned comma delimited (*.csv) dataset titled â Patients sociodemographic, clinical, psychosocial, and depressive symptom raw dataâ . It comprises patientsâ... -
A survey of thrombosis experts evaluating practices and opinions regarding ve...
Abstract Background Patients undergoing major abdominal surgery are at high risk for developing venous thromboembolism in the post-operative period. Current evidence-based... -
Horizontal gene transfer is not a hallmark of the human genome
Abstract Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al. as... -
Cardiovascular risk factors are major determinants of thrombotic risk in pati...
Abstract Background Patients with the lupus anticoagulant (LA) are at an increased risk of thrombotic events, which in turn increase the risk of death. Understanding the... -
Corticosteroid-free treatment of tocilizumab monotherapy for microscopic poly...
Objectives: To assess the efficacy of tocilizumab (TCZ) monotherapy for the remission induction of microscopic polyangiitis (MPA) in a prospective single-arm, single-center,... -
Additional file 2: Figure S3. of New insights into the pharmacokinetics and p...
Correlation of pre- and post-serum values at both timepoints. Correlation of pre- (black circle) and post- (white circle) NAT serum values at timepoint 0 and after 1 year (+1a).... -
Barriers in the implementation of isoniazid preventive therapy for people liv...
Abstract Background Isoniazid preventive therapy is a key public health intervention for the prevention of tuberculosis disease among people living with HIV. Despite the... -
Role of mesenchymal stem cells, their derived factors, and extracellular vesi...
Abstract Liver failure is a severe clinical syndrome with a poor prognosis. Mesenchymal stem cell (MSC) transplantation has emerged as a new intervention in treating liver... -
Six-month adherence to Statin use and subsequent risk of major adverse cardio...
Abstract Background The evidence of adherence to statin decreasing risk of major adverse cardiovascular events (MACEs) is still lack among patients discharged with acute... -
Ten important articles on noninvasive ventilation in critically ill patients ...
Abstract Background Noninvasive ventilation is used worldwide in many settings. Its effectiveness has been proven for common clinical conditions in critical care such as... -
Haploidentical allograft is superior to matched sibling donor allograft in er...
Abstract Background This study compared the effects of pre-transplantation minimal residual disease (pre-MRD) on outcomes in AML patients who underwent human leukocyte... -
Characterization and pathogenesis of aerosolized eastern equine encephalitis ...
Abstract Background Licensed antiviral therapeutics and vaccines to protect against eastern equine encephalitis virus (EEEV) in humans currently do not exist. Animal models that...
