-
Comparative analyses of the in vivo induction and transmission of α-synuclein...
Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central... -
Avelumab in patients with previously treated metastatic melanoma: phase 1b re...
Abstract Background We report phase 1b data from patients enrolled in the JAVELIN Solid Tumor clinical trial (NCT01772004) with unresectable stage IIIC or IV melanoma that had... -
Effects of cyclosporine A pretreatment of deceased organ donors on kidney gra...
Abstract Background Renal transplantation represents the treatment of choice of end-stage kidney disease. Delayed graft function (DGF) remains the most frequent complication... -
Inhibition of Salmonella Typhimurium adhesion, invasion, and intracellular su...
Abstract Salmonella enterica serovar Typhimurium infects intestinal epithelia and macrophages, which is prevented by inhibiting adhesion and cell invasion. This study aimed to... -
Multiphoton in vivo imaging with a femtosecond semiconductor disk laser
We use an ultrafast diode-pumped semiconductor disk laser (SDL) to demonstrate several applications in multiphoton microscopy. The ultrafast SDL is based on an optically pumped... -
Use of thiazide diuretics for the prevention of recurrent kidney calculi: a s...
Abstract Background Thiazide diuretics reduce the risk of recurrent kidney calculi in patients with kidney calculi or hypercalciuria. However, whether thiazide diuretics can... -
Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent periphera...
Abstract Background Chronic alcohol consumption is associated with neuroinflammation, neuronal damage, and behavioral alterations including addiction. Alcohol-induced... -
Production of human pro-relaxin H2 in the yeast Pichia pastoris
Abstract Background Initially known as the reproductive hormone, relaxin was shown to possess other therapeutically useful properties that include extracellular matrix... -
Association between hydroxocobalamin administration and acute kidney injury a...
Abstract Background The use of hydroxocobalamin has long been advocated for treating suspected cyanide poisoning after smoke inhalation. Intravenous hydroxocobalamin has however... -
A prospective, multi-centre, observational study to examine kidney disease pr...
Abstract Background The objective of this article is to describe the organisation of an international, clinical registry, the Chronic Kidney Disease Observational Database... -
Minoxidil versus placebo in the treatment of arterial wall hypertrophy in chi...
Abstract Background Insufficient elastin synthesis leads to vascular complications and arterial hypertension in children with Williams-Beuren syndrome. Restoring sufficient... -
Comparative effectiveness and safety of tranexamic acid plus diluted epinephr...
Abstract Background The standard protocol to achieve haemostasis during total hip arthroplasty (THA) is uncertain. Tranexamic acid plus diluted epinephrine (DEP) and tranexamic... -
Lower blood pressure and risk of cisplatin nephrotoxicity: a retrospective co...
Abstract Background The pathophysiological mechanisms of cisplatin nephrotoxicity include the reduction of renal blood flow, as well as tubular epithelial cell toxicity. The... -
Assessing the recovery from prerenal and renal acute kidney injury after trea...
Abstract Background Acute kidney injury (AKI) is an initial factor in many kidney disorders. Pre- and intra-renal AKI biomarkers have recently been reported. Recovery from AKI... -
Focusing light with orbital angular momentum by circular array antenna
We experimentally demonstrated focusing of light with orbital angular momentum (OAM) using an 8-element circular array of linear antennas. A spiral phase plate was used to... -
Bone marrow mesenchymal stromal cells attenuate silica-induced pulmonary fibr...
Abstract Background Pulmonary fibrosis induced by silica dust is an irreversible, chronic, and fibroproliferative lung disease with no effective treatment at present. Previous... -
Clinical efficacy of enhanced recovery after surgery in percutaneous nephroli...
Abstract Background To evaluate the feasibility, safety, applied value and efficacy of enhanced recovery after surgery (ERAS) for PCNL for the treatment of renal calculi.... -
Cost and economic burden of adverse events associated with metastatic melanom...
Objective: To estimate per-event cost and economic burden associated with managing the most common and/or severe metastatic melanoma (MM) treatment-related adverse events (AEs)... -
Practice patterns in transitioning patients from chronic kidney disease to di...
Abstract Background There are no guidelines for transitioning patients from chronic kidney disease stage 5 to hemodialysis. We conducted this study to determine if there are... -
The economic burden of asthma and chronic obstructive pulmonary disease and t...
Abstract Background Asthma and chronic obstructive pulmonary disease (COPD) are common chronic inflammatory respiratory diseases, which impose a substantial burden on healthcare...
