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Thermo-optic tuning and switching in SOI waveguide Fabry-Perot microcavities
Compact silicon-on-insulator (SOI) waveguide thermo-optically tunable Fabry-Perot microcavities with silicon/air Bragg mirrors are demonstrated. Quality factors of Q=4,584 are... -
CellTag Indexing: genetic barcode-based sample multiplexing for single-cell g...
Abstract High-throughput single-cell assays increasingly require special consideration in experimental design, sample multiplexing, batch effect removal, and data... -
Real-time handheld multispectral optoacoustic imaging
Multispectral optoacoustic tomography (MSOT) of functional and molecular contrast has the potential to find broad deployment in clinical practice. We have developed the first... -
Causal Interpretations of Black-Box Models
The fields of machine learning and causal inference have developed many concepts, tools, and theory that are potentially useful for each other. Through exploring the possibility... -
Ready, Set, Change! Development and usability testing of an online readiness ...
Abstract Background To address challenges related to selecting a valid, reliable, and appropriate readiness assessment measure in practice, we developed an online decision... -
GTZ: a fast compression and cloud transmission tool optimized for FASTQ files
Abstract Background The dramatic development of DNA sequencing technology is generating real big data, craving for more storage and bandwidth. To speed up data sharing and bring... -
Engineering yeast artificial core promoter with designated base motifs
Abstract Background Synthetic biology requires toolbox of promoters to finely tune gene expression levels for building up efficient cell factories. Yeast promoters owned... -
Correction to: Goats in the city: prevalence of Giardia duodenalis and Crypto...
In the original publication of this article [1] the supplementary file was missing two primers for the PCR reaction and the PCR conditions of Giardia and Cryptosporidium. In... -
Mapping the travel patterns of people with malaria in Bangladesh
Abstract Background Spread of malaria and antimalarial resistance through human movement present major threats to current goals to eliminate the disease. Bordering the Greater... -
The caloric and sugar content of beverages purchased at different store-types...
Abstract Background Following the 2014 sugary drinks tax implementation in Mexico, promising reduction in the volume of purchases of taxed beverages were observed overall and at... -
Inherent bacterial DNA contamination of extraction and sequencing reagents ma...
Abstract Background The advent and use of highly sensitive molecular biology techniques to explore the microbiota and microbiome in environmental and tissue samples have... -
GGDonto ontology as a knowledge-base for genetic diseases and disorders of gl...
Abstract Background Inherited mutations in glyco-related genes can affect the biosynthesis and degradation of glycans and result in severe genetic diseases and disorders. The... -
Correction to: Genetic diversity of the Thao people of Taiwan using Y-chromos...
Following publication of the original article [1], we have been notified that Additional file 3 was published with track changes. -
The intestinal microbiota regulates host cholesterol homeostasis
Abstract Background Management of blood cholesterol is a major focus of efforts to prevent cardiovascular diseases. The objective of this study was to investigate how the gut... -
Genome-wide transcription start site mapping of Bradyrhizobium japonicum grow...
Abstract Background Differential RNA-sequencing (dRNA-seq) is indispensable for determination of primary transcriptomes. However, using dRNA-seq data to map transcriptional... -
A method for extracting electronic patient record data from practice manageme...
Abstract Background Data extracted from electronic patient records (EPRs) within practice management software systems are increasingly used in veterinary research. The use of... -
Controllable Growth of the Graphene from Millimeter-Sized Monolayer to Multil...
Abstract As is well established, mastery to precise control of the layer number, stacking order of graphene, and the size of single-crystal monolayer graphene is very important... -
Structural and mechanistic analysis of engineered trichodiene synthase enzyme...
Trichoderma spp. are well-known bioagents for the plant growth promotion and pathogen suppression. The beneficial activities of the fungus Trichoderma spp. are attributed to... -
GPCR and IR genes in Schistosoma mansoni miracidia
Abstract Background Schistosoma species are responsible for the disease schistosomiasis, a highly prevalent helminthic disease that requires a freshwater snail as intermediate... -
Using synthetic biology to increase nitrogenase activity
Abstract Background Nitrogen fixation has been established in protokaryotic model Escherichia coli by transferring a minimal nif gene cluster composed of 9 genes (nifB, nifH,...