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Omalizumab in patients with severe asthma and persistent sputum eosinophilia
Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who... -
Differences in reported sepsis incidence according to study design: a literat...
Abstract Background Sepsis and severe sepsis are common conditions in hospital settings, and are associated with high rates of morbidity and mortality, but reported incidences... -
Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate...
Abstract Background Dexketoprofen trometamol plus tramadol hydrochloride is a new oral combination of two analgesics, which have different mechanisms of action for the treatment... -
Assessment of blood levels of heavy metals including lead and manganese in he...
Abstract Background Exposure to environmental heavy metals is common among African children. Although many of these metals are known neurotoxicants, to date, monitoring of this... -
Integrative assessment of brain and bone invasion in meningioma patients
Abstract Background Various prognostic factors have been suggested in meningioma patients including WHO grading, brain invasion and bone involvement, for instance. Brain... -
Erectile dysfunction and associated factors among men with diabetes mellitus ...
Abstract Objective Prevalence of erectile dysfunction (ED) in diabetic men is considerably high but it is often underdiagnosed and undermanaged. There were no data available... -
Comparative utility of frailty to a general prognostic score in identifying p...
Abstract Background Current guidelines recommend considering life expectancy before aortic valve replacement (AVR). We compared the performance of a general mortality index, the... -
The impact of disease severity on paradoxical association between body mass i...
Abstract Background Association between high body mass index (BMI) and survival benefit is confounded by comorbid conditions such as nutritional status and inflammation.... -
Impact of radiographer immediate reporting of chest X-rays from general pract...
Abstract Background Diagnostic capacity and suboptimal logistics are consistently identified as barriers to timely diagnosis of cancer, especially lung cancer. Immediate chest... -
Clinical determinants of the severity of Middle East respiratory syndrome (ME...
Abstract Background While the risk of severe complications of Middle East respiratory syndrome (MERS) and its determinants have been explored in previous studies, a systematic... -
Non-alcoholic fatty liver disease as a risk factor for cholangiocarcinoma: a ...
Abstract Background Non-alcoholic fatty liver disease (NAFLD) has been recently identified as a risk factor of gastrointestinal tract cancers, especially hepatocellular... -
Plasma levels of increased miR-195-5p correlates with the sFLT-1 levels in pr...
Although the role of soluble fms-like tyrosine kinase 1 (sFLT-1) in preeclampsia is well-established, the mechanism related to its synthesis remains poorly understood. We... -
N-acetylcysteine exposure is associated with improved survival in anti-nuclea...
Abstract Background Mortality is similarly high among individuals with usual interstitial pneumonia (UIP) due to idiopathic pulmonary fibrosis (IPF) and interstitial pneumonia... -
Expression of ACE2 and a viral virulence-regulating factor CCN family member ...
Abstract It has been reported that coronavirus disease 2019 (COVID-19) causes not only pneumonia but also systemic inflammations including central nervous system (CNS)... -
The effects of green cardamom on blood glucose indices, lipids, inflammatory ...
Abstract Background The relationship between dietary components and nonalcoholic fatty liver disease (NAFLD) needs to be further investigated. The potential health benefits of... -
Feasibility and acceptance of exercise recommendations (10,000 steps a day) w...
Abstract Background Benefits of exercise to prevent non-communicable diseases are well-documented. Limited data exists to promote physical activity in healthy but sedentary... -
Status of metered dose inhaler technique among patients with asthma and its e...
Abstract Objective In Asthma management, poor handling of inhalation devices and wrong inhalation technique are associated with decreased medication delivery and poor disease... -
Correlates of employment status in individuals with asthma: a cross-sectional...
Abstract Background This study aims to elucidate factors that among adults with asthma are associated with working full-time. Methods This cross-sectional survey of 2613... -
Blood groups A and AB are associated with increased gastric cancer risk: evid...
Abstract Background The association of ABO blood groups with gastric cancer risk was proposed decades ago, but the results have been inconsistent. Methods We used two single... -
The neuroregenerative effects of topical decorin on the injured mouse cornea
Abstract Background The cornea is innervated with a rich supply of sensory nerves that play important roles in ocular surface health. Any injury or pathology of the corneal...
