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Oxidative stress and premature senescence in corneal endothelium following pe...
Abstract Background The purpose of this study was to address the question of how the premature senescence process may affect corneal endothelium after penetrating keratoplasty,... -
High-resolution dual-modality photoacoustic ocular imaging
We have developed a prototype ocular imaging system that integrates optical-resolution photoacoustic microscopy and high-frequency ultrasound imaging. The system can perform... -
Polarization-sensitive swept-source optical coherence tomography with continu...
We present fiber-based polarization-sensitive swept-source optical coherence tomography (SS-OCT) based on continuous source polarization modulation. The light source is a... -
Noninvasive multimodal imaging in diagnosing polypoidal choroidal vasculopathy
Abstract Purpose To investigate the diagnostic accuracy of noninvasive multimodal imaging methods in diagnosing polypoidal choroidal vasculopathy (PCV) and distinguishing PCV... -
Minimal internal limiting membrane peeling with ILM flap technique for idiopa...
Abstract Background Internal limiting membrane (ILM) peeling increases the idiopathic macular hole (IMH) closure rate but causes the inner retina dimplings. This study is to... -
Fiber-based polarization-sensitive OCT for birefringence imaging of the anter...
We demonstrate a prototype system of polarization-sensitive optical coherence tomography (PS-OCT) designed for clinical studies of the anterior eye segment imaging. The system... -
Diagnostic ability of macular ganglion cell asymmetry in Preperimetric Glaucoma
Abstract Background To evaluate the diagnostic ability of macular ganglion cell asymmetry to diagnose preperimetric glaucoma (PPG), using Cirrus spectral domain optical... -
Three-dimensional and high-speed swept-source optical coherence tomography fo...
A two- and three-dimensional swept source optical coherence tomography (SS-OCT) system, which uses a ready-to-ship scanning light source, is demonstrated. The light source has a... -
Three dimensional OCT images from retina and skin
We demonstrate the functionality of an en-face optical coherence tomography (OCT) system with images from the retina and skin. En-face images collected at different depths are... -
Multi-modal adaptive optics system including fundus photography and optical c...
We present a new compact multi-modal imaging prototype that combines an adaptive optics (AO) fundus camera with AO-optical coherence tomography (OCT) in a single instrument. The... -
Phase-sensitive imaging of the outer retina using optical coherence tomograph...
The cone photoreceptor’s outer segment (OS) experiences changes in optical path length, both in response to visible stimuli and as a matter of its daily course of renewal and... -
Adaptive optics parallel near-confocal scanning ophthalmoscopy
We present an adaptive optics parallel near-confocal scanning ophthalmoscope (AOPCSO) using a digital micromirror device (DMD). The imaging light is modulated to be a line of... -
In vivo high-resolution video-rate spectral-domain optical coherence tomograp...
An ultra-high-speed spectral-domain optical coherence tomography system (SD-OCT) was developed for imaging the human retina and optic nerve in vivo at a sustained depth profile... -
Reduction of corneal epithelial thickness during medical treatment for myopic...
Abstract Background To evaluate corneal epithelial thickness change during medical treatment for eyes with myopic regression after femtosecond laser-assisted in situ... -
OCT elastography: imaging microscopic deformation and strain of tissue
Optical coherence tomography (OCT) has been applied to the study of the microscopic deformation of biological tissue under compressive stress. We describe the hardware and...