-
Novel mutation in the CHST6 gene causes macular corneal dystrophy in a black ...
Abstract Background Macular corneal dystrophy (MCD) is a rare autosomal recessive disorder that is characterized by progressive corneal opacity that starts in early childhood... -
Early-life exposure to three size-fractionated ultrafine and fine atmospheric...
Abstract Background Epidemiological studies have suggested that elevated levels of air pollution contribute to an increased incidence or severity of asthma. Although late-onset... -
Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats...
Abstract Background Recurrent and persistent infections are known to affect airways of patients with Primary Immunodeficiency despite appropriate replacement immunoglobulin... -
Examining the role of unmeasured confounding in mediation analysis with genet...
Abstract Background In mediation analysis if unmeasured confounding is present, the estimates for the direct and mediated effects may be over or under estimated. Most methods... -
TSS-EMOTE, a refined protocol for a more complete and less biased global mapp...
Abstract Background Bacteria rely on efficient gene regulatory mechanisms to switch between genetic programs when they are facing new environments. Although this regulation can... -
Enhanced electrical power generation using flame-oxidized stainless steel ano...
Abstract Background Carbon-based materials are commonly used as anodes in microbial fuel cells (MFCs), whereas metal and metal-oxide-based materials are not used frequently... -
The Dictyostelium discoideum homologue of Twinkle, Twm1, is a mitochondrial D...
Abstract Background DNA replication requires contributions from various proteins, such as DNA helicases; in mitochondria Twinkle is important for maintaining and replicating... -
Three-Dimensional CuO/TiO2 Hybrid Nanorod Arrays Prepared by Electrodepositio...
Abstract Three-dimensional (3D) CuO/TiO2 hybrid heterostructure nanorod arrays (NRs) with noble-metal-free composition, fabricated by template-assisted low-cost processes, were... -
Characterisation of a niche-specific excretory–secretory peroxiredoxin from t...
Abstract Background The primary cause of parasitic gastroenteritis in small ruminants in temperate regions is the brown stomach worm, Teladorsagia circumcincta. Host immunity to... -
Meta-analysis of human gene expression in response to Mycobacterium tuberculo...
Abstract Background With the global emergence of multi-drug resistant strains of Mycobacterium tuberculosis, new strategies to treat tuberculosis are urgently needed such as... -
Past and new challenges for malaria control and elimination: the role of oper...
Abstract This meeting report presents the outcomes of a workshop held in Bangkok on December 1st 2014, where the following challenges were discussed: the threat of resistance to... -
miR-124 attenuates Japanese encephalitis virus replication by targeting DNM2
Abstract Background Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that causes acute viral encephalitis in humans. Pigs are important amplifier hosts of JEV.... -
Diverse effects of nitric oxide reductase NorV on Aeromonas hydrophila virule...
Abstract NorV has been known to be an anaerobic nitric oxide reductase associated with nitric oxide (NO) detoxification. Recently, we showed that the norV gene of Aeromonas... -
Neutrophil extracellular traps induce aggregation of washed human platelets i...
Abstract Background The release of neutrophil extracellular traps (NETs), a mesh of DNA, histones and neutrophil proteases from neutrophils, was first demonstrated as a host... -
Complex and dynamic transcriptional changes allow the helminth Fasciola gigan...
Abstract Background The tropical liver fluke, Fasciola gigantica causes fasciolosis, an important disease of humans and livestock. We characterized dynamic transcriptional... -
Long-term outdoor air pollution and DNA methylation in circulating monocytes:...
Abstract Background DNA methylation may mediate effects of air pollution on cardiovascular disease. The association between long-term air pollution exposure and DNA methylation... -
RNA polymerase II depletion promotes transcription of alternative mRNA species
Abstract Background Cells respond to numerous internal and external stresses, such as heat, cold, oxidative stress, DNA damage, and osmotic pressure changes. In most cases, the... -
Differential expression of hemolysin genes in weakly and strongly hemolytic B...
Abstract Background Swine dysentery (SD) is a diarrheal disease in fattening pigs that is caused by the strongly hemolytic species Brachyspira (B.) hyodysenteriae, B. hampsonii... -
Virulence factor RNA transcript expression in the Leishmania Viannia subgenus...
Abstract Background Leishmania RNA virus-1 (LRV1) is a double-stranded RNA virus identified in 20–25% of Viannia—species endemic to Latin America, and is believed to accelerate... -
Characterization of the regulation mechanism of grapevine microRNA172 family ...
Abstract Background Grapevine (Vitis vinifera L.), which has important nutritional values and health benefits, is one of the most economically important fruit crops cultivated...
