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Ouabain prevents pathological cardiac hypertrophy and heart failure through a...
Abstract Background Use of low doses of digitalis to prevent the development of heart failure was advocated decades ago, but conflicting results of early animal studies... -
TFAP2A is a component of the ZEB1/2 network that regulates TGFB1-induced epit...
Abstract Background The transition between epithelial and mesenchymal phenotypes (EMT) occurs in a variety of contexts. It is critical for mammalian development and it is also... -
A primer on the use of mouse models for identifying direct sex chromosome eff...
Abstract In animals with heteromorphic sex chromosomes, all sex differences originate from the sex chromosomes, which are the only factors that are consistently different in... -
A self-marker-like protein governs hemocyte allorecognition in Halocynthia ro...
Abstract Background Self-incompatibility, fusion/non-fusion reactions, and contact reactions (CRs) have all been identified as allorecognition phenomena in ascidians. CR is a... -
Toll-Like Receptor 4 Engagement Inhibits Adenosine 5′-Monophosphate-Activated...
Abstract Despite the potent antiinflammatory effects of pharmacologically induced adenosine 5′-monophosphate kinase (AMPK) activation on Toll-like receptor 4 (TLR4)-induced... -
Classifying human promoters by occupancy patterns identifies recurring sequen...
Abstract Background Characterizing recurring sequence patterns in human promoters has been a challenging undertaking even nowadays where a near-complete overview of promoters... -
Leptin receptor signaling is required for high-fat diet-induced atrophic gast...
Abstract Background Obesity increases the risk for malignancies in various tissues including the stomach. Atrophic gastritis with precancerous lesions is an obesity-associated... -
A novel Sugarcane bacilliform virus promoter confers gene expression preferen...
Abstract Background Saccharum species such as sugarcane and energy cane are key players in the expanding bioeconomy for sugars, bioenergy, and production of high-value proteins.... -
Gender disparities and psychological distress among humanitarian migrants in ...
Abstract Background The role of migration pathway (refugees vs. asylum seekers) is seldom addressed in extant literature that looks at gender and mental health of humanitarian... -
Correction to: SKIP controls flowering time via the alternative splicing of S...
Upon publication of the original article [1], the authors noticed that they omitted Additional file 16: Table S10 from the Additional file list. Additional file 16: Table S10... -
Synergistic toxicity in an in vivo model of neurodegeneration through the co-...
Abstract Although it has been suggested that the co-expression of multiple pathological proteins associated with neurodegeneration may act synergistically to induce more... -
Comparative RNA-seq based transcriptomic analysis of bud dormancy in grape
Abstract Background Bud dormancy is an important biological phenomenon of perennial plants that enables them to survive under harsh environmental circumstances. Grape (Vitis... -
Developmental basis for intestinal barrier against the toxicity of graphene o...
Abstract Background Intestinal barrier is crucial for animals against translocation of engineered nanomaterials (ENMs) into secondary targeted organs. However, the molecular... -
A p53/TIAF1/WWOX triad exerts cancer suppression but may cause brain protein ...
Abstract Background Tumor suppressor WWOX physically binds p53 and TIAF1 and together induces apoptosis and tumor suppression. To understand the molecular action, here we...
