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The cotton GhWIN2 gene activates the cuticle biosynthesis pathway and influen...
Abstract Background Metabolic pathways are interconnected and yet relatively independent. Genes involved in metabolic modules are required for the modules to run. Study of the... -
High carriage of adherent invasive E. coli in wildlife and healthy individuals
Abstract Background Adherent invasive Escherichia coli (AIEC) are suspected to be involved in the pathogenesis of inflammatory bowel diseases. Since AIEC was first described in... -
Characterization of the regulation mechanism of grapevine microRNA172 family ...
Abstract Background Grapevine (Vitis vinifera L.), which has important nutritional values and health benefits, is one of the most economically important fruit crops cultivated... -
Endonuclease G takes part in AIF-mediated caspase-independent apoptosis in My...
Abstract Mycobacterium bovis, the causative agent of bovine tuberculosis encodes different virulence mechanisms to survive inside of host cells. One of the possible outcomes in... -
The transcriptome of Candida albicans mitochondria and the evolution of organ...
Abstract Background Yeasts show remarkable variation in the organization of their mitochondrial genomes, yet there is little experimental data on organellar gene expression... -
Non-target screening of organic pollutants and target analysis of halogenated...
Abstract Background The 16 priority polycyclic aromatic hydrocarbons (PAHs) issued by US Environmental protection agency are a major focus in atmosphere in previous studies.... -
The impact of achieving a sustained virological response with direct-acting a...
Abstract Background Autotaxin (ATX) is an emerging biomarker for liver fibrosis. Achievement of sustained virological response (SVR) by direct-acting antivirals (DAAs) results... -
Crosstalk between chromatin structure, cohesin activity and transcription
Abstract Background A complex interplay between chromatin and topological machineries is critical for genome architecture and function. However, little is known about these... -
Mandible evolution in the Scarabaeinae (Coleoptera: Scarabaeidae) and adaptat...
Abstract Introduction The astonishing spectrum of scarabaeine lifestyles makes them an attractive group for studies in entomology and evolutionary biology. As a result of... -
Association of CXCL10 and CXCL13 levels with disease activity and cutaneous m...
Abstract Introduction C-X-C motif chemokine 10 (CXCL10) is produced in response to interferon-γ, and tumor necrosis factor-α (TNF-α) triggers the accumulation of activated... -
Amikacin pharmacokinetic/pharmacodynamic in intensive care unit: a prospectiv...
Abstract Background Aminoglycosides have a concentration-dependent therapeutic effect when peak serum concentration (Cmax) reaches eight to tenfold the minimal inhibitory... -
De novo transcriptome sequencing of radish (Raphanus sativus L.) fleshy roots...
Abstract Background The HongXin radish (Raphanus sativus L.), which contains the natural red pigment (red radish pigment), is grown in the Fuling district of Chongqing City.... -
Wnt signal transduction pathways: modules, development and evolution
Abstract Background Wnt signal transduction pathway (Wnt STP) is a crucial intracellular pathway mainly due to its participation in important biological processes, functions,... -
Chaperone activity of serine protease HtrA of Helicobacter pylori as a crucia...
Abstract Background Serine protease HtrA exhibits both proteolytic and chaperone activities, which are involved in cellular protein quality control. Moreover, HtrA is an... -
Long-read sequencing uncovers a complex transcriptome topology in varicella z...
Abstract Background Varicella zoster virus (VZV) is a human pathogenic alphaherpesvirus harboring a relatively large DNA molecule. The VZV transcriptome has already been... -
Assessment of the significance of patent-derived information for the early id...
Abstract Background Patents are an important source of information for effective decision making in drug discovery. Encouragingly, freely accessible patent-chemistry databases... -
A mitochondrial division inhibitor, Mdivi-1, inhibits mitochondrial fragmenta...
Abstract Background Kainic acid (KA)-induced excitotoxicity promotes cytoplasmic calcium accumulation, oxidative stress, and apoptotic signaling, leading to hippocampal neuronal... -
The development of a survey instrument to measure the barriers to the conduct...
Abstract Background As Complementary and Alternative medicine (CAM) grows in popularity, there is overt recognition for research evidence to inform clinical practice. While... -
Newborn hearing screening protocol in tuscany region
Abstract Background Newborn hearing screening has to be considered the first step of a program for the identification, diagnosis, treatment and habilitation/rehabilitation of... -
Nuclear localization of Newcastle disease virus matrix protein promotes virus...
Abstract Nuclear localization of paramyxovirus proteins is crucial for virus life cycle, including the regulation of viral replication and the evasion of host immunity. We...
