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Re-programming of Pseudomonas syringae pv. actinidiae gene expression during ...
Abstract Background Pseudomonas syringae is a widespread bacterial species complex that includes a number of significant plant pathogens. Amongst these, P. syringae pv.... -
Involvement of Hdac3-mediated inhibition of microRNA cluster 17-92 in broncho...
Abstract Background The incidence of bronchopulmonary dysplasia (BPD), a chronic lung disease of newborns, has been paradoxically rising despite medical advances. Histone... -
GSTU43 gene involved in ALA-regulated redox homeostasis, to maintain coordina...
Abstract Background Exogenous 5-aminolevulinic acid (ALA) positively regulates plants chlorophyll synthesis and protects them against environmental stresses, although the... -
Comparison of two methods of collecting healthcare usage data in chiropractic...
Abstract Background The use of patient-reported questionnaires to collect information on costs associated with routine healthcare services, such as chiropractic, represents a... -
The interferon-induced antiviral protein PML (TRIM19) promotes the restrictio...
Abstract Background The promyelocytic leukemia (PML) protein, a type I interferon (IFN-I)-induced gene product and a member of the tripartite motif (TRIM) family, modulates the... -
Evidence of cAMP involvement in cellobiohydrolase expression and secretion by...
Abstract Background The signaling second messenger cyclic AMP (cAMP) regulates many aspects of cellular function in all organisms. Previous studies have suggested a role for... -
Evaluating the efficacy of dexamethasone in the treatment of patients with pe...
Abstract Background Although much has evolved in our understanding of the pathogenesis and factors affecting outcome of patients with acute respiratory distress syndrome (ARDS),... -
Glossogyne tenuifolia (Hsiang-ju) extract suppresses T cell activation by inh...
Abstract Background Glossogyne tenuifolia (GT) (Hsiang-ju) is a Chinese herbal medicine previously exhibited an anti-inflammatory activity. This study aimed to investigate the... -
Bacillus subtilis 5′-nucleotidases with various functions and substrate speci...
Abstract Background In Escherichia coli, nagD, yrfG, yjjG, yieH, yigL, surE, and yfbR encode 5′-nucleotidases that hydrolyze the phosphate group of 5′-nucleotides. In Bacillus... -
Type 2 diabetes increases oocyte mtDNA mutations which are eliminated in the ...
Abstract Background Diabetes induces many complications including reduced fertility and low oocyte quality, but whether it causes increased mtDNA mutations is unknown. Methods... -
Post renal transplant anemia: severity, causes and their association with gra...
Abstract Background Post transplantation anemia (PTA) is common among kidney transplant patients. PTA is associated with increased graft loss and in most studies with increased... -
Quorum sensing of Streptococcus mutans is activated by Aggregatibacter actino...
Abstract Background The oral cavity is inhabited by complex microbial communities forming biofilms that can cause caries and periodontitis. Cell-cell communication might play an... -
DNA-binding sequence specificity of DUX4
Abstract Background Misexpression of the double homeodomain transcription factor DUX4 results in facioscapulohumeral muscular dystrophy (FSHD). A DNA-binding consensus with two... -
Promoting deceased organ and tissue donation registration in family physician...
Abstract Background There is a worldwide shortage of organs available for transplant, leading to preventable mortality associated with end-stage organ disease. While most... -
Α de novo 3.8-Mb inversion affecting the EDA and XIST genes in a heterozygous...
Abstract Background In mammals, hypohidrotic ectodermal dysplasia (HED) is a genetic disorder that is characterized by sparse hair, tooth abnormalities, and defects in cutaneous... -
Promoter activity of Merkel cell Polyomavirus variants in human dermal fibrob...
Abstract Background Merkel cell polyomavirus (MCPyV) is a human polyomavirus that establishes a life-long harmless infection in most individuals, with dermal fibroblasts... -
Innate immune activation of astrocytes impairs neurodevelopment via upregulat...
Abstract Background Polyriboinosinic-polyribocytidylic acid (polyI:C) triggers a strong innate immune response that mimics immune activation by viral infections. Induction of... -
Medication use in juvenile uveitis patients enrolled in the Childhood Arthrit...
Abstract Background There is not yet a commonly accepted, standardized approach in the treatment of juvenile idiopathic uveitis when initial steroid therapy is insufficient. We... -
Epstein-Barr virus lytic infection promotes activation of Toll-like receptor ...
Abstract Background Monocytes/macrophages are activated in several autoimmune diseases, including systemic sclerosis (scleroderma; SSc), with increased expression of interferon... -
Mild decrease in heart rate during early phase of targeted temperature manage...
Abstract Background The association between isolated admission heart rate (HR) and prognosis has been discussed, but not that between gross HR change and neurological outcome in...
