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Use of diagnostic tests and the appropriateness of the treatment decision in ...
Abstract Background Inappropriate prescription of antibiotics is the leading driver of antimicrobial resistance (AMR). The majority of antibiotics are prescribed in primary... -
Adherence to guidelines across different specialties to prevent infections in...
Abstract Background Substantial numbers of patients are now receiving either immunosuppressive therapies or chemotherapy. There are significant risks in such patients of... -
Impact of antibiotic therapy on the development and response to treatment of ...
Abstract Background The gut microbiome impacts the efficacy of immune checkpoint inhibitor (ICI) therapy and the development of ICI-mediated diarrhea and/or colitis (IMDC).... -
Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate...
Abstract Background Dexketoprofen trometamol plus tramadol hydrochloride is a new oral combination of two analgesics, which have different mechanisms of action for the treatment... -
Prevalence of nasal colonization by methicillin-resistant Staphylococcus aure...
Abstract Objective The purpose of this study is to investigate the prevalence of MRSA among people living with HIV/AIDS (PLHA) being monitored in a tertiary outpatient hospital... -
Prevalence and in-hospital outcomes of diabetes among patients with acute cor...
Abstract Background Guidelines have classified patients with acute coronary syndrome (ACS) and diabetes as a special population, with specific sections presented for the... -
Evaluation of virtual patient cases for teaching diagnostic and management sk...
Abstract Objective The virtual patient (VP) is a computer program that simulates real-life clinical scenarios and allows learners to make diagnostic and therapeutic decisions in... -
Factors influencing the time between onset of illness and specimen collection...
Abstract Background Listeriosis is an opportunistic bacterial infection caused by Listeria monocytogenes and predominantly affects people who are immunocompromised. Due to its... -
Agreement of claims-based methods for identifying sepsis with clinical criter...
Abstract Background Claims-based algorithms are commonly used to identify sepsis in health services research because the laboratory features required to define clinical criteria... -
ATLANTIS: a randomised multi-arm phase II biomarker-directed umbrella screeni...
Abstract Background Metastatic urothelial cancer (UC) is the eighth most common cause of cancer death in the UK. Standard first-line treatment, for most patients, is cytotoxic... -
Relationship between viral dose and outcome of infection in Atlantic salmon, ...
Abstract Salmonid alphavirus subtype 3 (SAV3) causes pancreas disease (PD) and adversely affects salmonid aquaculture in Europe. A better understanding of disease transmission... -
Diabetic retinopathy is associated with the presence and burden of subclinica...
Abstract Background Cardiovascular (CV) disease due to atherosclerosis is a major cause of morbidity and mortality in adult patients with diabetes, either type 1 or type 2... -
Production results from piglets vaccinated in a field study in Spain with a T...
Abstract Background PRRS is a viral disease of pigs and sows that is one of the most costly to the pig industry worldwide. The disease can be controlled by focusing on different... -
Pertussis outbreak investigation of Mekdela district, South Wollo zone, Amhar...
Abstract Background Pertussis is a highly contagious respiratory illness caused by Bordetella pertussis. It is one of the most common vaccine-preventable bacterial infections... -
Burden of pneumocystis pneumonia in HIV-infected adults in sub-Saharan Africa...
Abstract Background Seroprevalence data and clinical studies in children suggest that the burden of pneumocystis pneumonia (PCP) in Africa may be underestimated. We performed a... -
Divergent transcriptomic responses underlying the ranaviruses-amphibian inter...
Abstract Background Ranaviruses (family Iridoviridae, nucleocytoplasmic large DNA viruses) have been reported as promiscuous pathogens of cold-blooded vertebrates. Rana grylio... -
Distribution of nickel and chromium containing particles from tattoo needle w...
Abstract Background Allergic reactions to tattoos are amongst the most common side effects occurring with this permanent deposition of pigments into the dermal skin layer. The... -
The impairment of small nerve fibers in severe sepsis and septic shock
Abstract Background A decrease of small nerve fibers in skin biopsies during the course of critical illness has been demonstrated recently. However, the diagnostic use of skin... -
Expression of ACE2 and a viral virulence-regulating factor CCN family member ...
Abstract It has been reported that coronavirus disease 2019 (COVID-19) causes not only pneumonia but also systemic inflammations including central nervous system (CNS)... -
Onychomycosis in diabetic patients in Fako Division of Cameroon: prevalence, ...
Abstract Background Onychomycosis is an infection of the nail unit by a fungus. This is a very common infection amongst diabetics. Its occurrence among diabetics in Fako...