354 items found

Licenses: License Not Specified Tags: 39999 Chemical Sciences not elsewhere classified Cell Biology Pharmacology Science Policy Groups: Datacite figshare Types: other

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    Dried blood spot versus venous blood sampling for phenylalanine and tyrosine

    Abstract Background This study investigated the agreement between various dried blood spot (DBS) and venous blood sample measurements of phenylalanine and tyrosine...
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    Erythropoietin as an add-on treatment for cognitive side effects of electroco...

    Abstract Background Electroconvulsive therapy (ECT) is the most effective treatment for severe depression, but its use is impeded by its cognitive side effects. Novel treatments...
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    Serum progesterone distribution in normal pregnancies compared to pregnancies...

    Abstract Background Progesterone is a critical hormone in early pregnancy. A low level of serum progesterone is associated with threatened miscarriage. We aim to establish the...
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    Combining adverse pregnancy and perinatal outcomes for women exposed to antie...

    Abstract Background Application of latent variable models in medical research are becoming increasingly popular. A latent trait model is developed to combine rare birth defect...
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    A systematic review of non-antibiotic measures for the prevention of urinary ...

    Abstract Background Urinary tract infections (UTIs) are common in pregnancy and account for the highest proportion of primary care antibiotic prescriptions issued to pregnant...
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    Development of a core outcome set for diabetes after pregnancy prevention int...

    Abstract Background Gestational diabetes mellitus (GDM) increases the risk of adverse short- and long-term outcomes, including development of type 2 diabetes. The US Diabetes...
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    Removal of the product from the culture medium strongly enhances free fatty a...

    Abstract Background Cyanobacterial mutants engineered for production of free fatty acids (FFAs) secrete the products to the medium and hence are thought to be useful for biofuel...
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    Differential expression of E-type prostanoid receptors 2 and 4 in microglia s...

    Abstract Background Cyclooxygenase-2 (COX-2) is induced under inflammatory conditions, and prostaglandin E2 (PGE2) is one of the products of COX activity. PGE2 has pleiotropic...
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    Dimethyl fumarate attenuates reactive microglia and long-term memory deficits...

    Abstract Background Systemic inflammation is associated with increased cognitive decline and risk for Alzheimer’s disease. Microglia (MG) activated during systemic inflammation...
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    Periostin involved in the activated hepatic stellate cells-induced progressio...

    Abstract Background Incomplete thermal ablation may induce invasiveness of hepatocellular carcinoma (HCC). Here, we investigated whether activated hepatic stellate cells (HSCs)...
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    Aerosolized antibiotics for ventilator-associated pneumonia: a pairwise and B...

    Abstract Background Aerosolized antibiotics have been proposed as a novel and promising treatment option for the treatment of ventilator-associated pneumonia (VAP). However, the...
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    M1-like tumor-associated macrophages activated by exosome-transferred THBS1 p...

    Abstract Background Treatment strategies targeting tumor-associated macrophages (TAMs) have been proposed in cancer areas. The functional alterations of macrophages in the...
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    Amorphous silica nanoparticles induce malignant transformation and tumorigene...

    Rapid development and deployment of engineered nanomaterials, such as amorphous silica nanoparticles (SiNPs) in various commercial and biomedical applications have raised...
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    Prenatal alcohol exposure and infant gross motor development: a prospective c...

    Abstract Background Maternal alcohol consumption in pregnancy may have adverse effects on child gross motor (GM) development. There have been few human studies on this topic,...
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    Creation of reference DNA barcode library and authentication of medicinal pla...

    Abstract Background Ayurveda is a system of traditional medicine that originated in ancient India, and it is still in practice. Medicinal plants are the backbone of Ayurveda,...
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    Minimally invasive dual incision with mini plate internal fixation improves o...

    Abstract Background Calcaneal Sanders type III or higher fractures traditionally have been treated with open reduction and internal fixation (ORIF); however, ORIF has associated...
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    ConFIRM trial - conversion of in vitro fertilization cycles to intrauterine i...

    Abstract Background To date, there is no consensus on the ideal management strategy of patients with poor ovarian response (POR) to controlled ovarian stimulation (COS) for in...
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    Effect of hCMSCs and liraglutide combination in ALI through cAMP/PKAc/β-caten...

    Abstract Background ALI/ARDS is the major cause of acute respiratory failure in critically ill patients. As human chorionic villi-derived MSCs (hCMSCs) could attenuate ALI in...
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    Obstetric triage systems: a systematic review of measurement properties (Clin...

    Abstract Background Since labor and delivery units often serve as emergency units for pregnant women, the use of obstetric triage systems with poor or inadequate quality can...
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    cAMP- and cGMP-elevating agents inhibit GPIbα-mediated aggregation but not GP...

    Abstract Background The glycoprotein (GP) Ib-IX-V complex is a unique platelet plasma membrane receptor, which is essential for platelet adhesion and thrombus formation. GPIbα,...