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Risk factors for poor asthma control and impaired quality of life in a Caribb...
Objective: Asthma, a major cause of disability and reduced quality of life, has a high global prevalence and burden of death. Despite the propitious guidelines, a substantial... -
The repeatability of superficial retinal vessel density measurements in eyes ...
Abstract Background To investigate the repeatability of superficial retinal vessel density measurements in healthy eyes with long axial length (AL) using optical coherence... -
Cohort profile: the German Diabetes Study (GDS)
Abstract Background The German Diabetes Study (GDS) is a prospective longitudinal cohort study describing the impact of subphenotypes on the course of the disease. GDS aims at... -
Cardiovascular efficacy of sitagliptin in patients with diabetes at high risk...
Abstract Background Gliptins should have beneficial effects beyond glycemic control, potentially on the pathophysiology of cardiovascular (CV) diseases, with some basic studies... -
Trabecular bone score may indicate chronic kidney disease-mineral and bone di...
Abstract Background In the general population, the trabecular bone score (TBS) represents the bone microarchitecture and predicts fracture risk independent of bone mineral... -
A review on the salt bridge ASP177-ARG163 (O–N) of wild-type rabbit prion pro...
A review on the salt bridge ASP177-ARG163 (O–N) of wild-type rabbit prion protein -
Effect of mechanical power on intensive care mortality in ARDS patients
Abstract Background In ARDS patients, mechanical ventilation should minimize ventilator-induced lung injury. The mechanical power which is the energy per unit time released to... -
Murine sepsis phenotypes and differential treatment effects in a randomized t...
Abstract Background Clinical and biologic phenotypes of sepsis are proposed in human studies, yet it is unknown whether prognostic or drug response phenotypes are present in... -
Comparative analysis of the root transcriptomes of cultivated and wild rice v...
Abstract Background Magnaporthe oryzae, the causal fungus of rice blast disease, negatively impacts global rice production. Wild rice (Oryza rufipogon), a relative of cultivated... -
Clinical factors associated with the recovery of cardiovascular autonomic neu...
Abstract Background Cardiovascular autonomic neuropathy (CAN) is a major cause of morbidity and mortality in diabetes patients. Although several risk factors for CAN progression... -
Assessment of eye length changes in accommodation using dynamic extended-dept...
It has been suggested that accommodation induces increases in axial eye length which could contribute to the development of myopia. However, it is debated whether changes in eye... -
Sprifermin (rhFGF18) modulates extracellular matrix turnover in cartilage exp...
Abstract Background Sprifermin (recombinant human fibroblast growth factor 18) is in clinical development as a potential disease-modifying osteoarthritis drug (DMOAD). In vitro... -
Isolated unilateral temporalis muscle hypertrophy in a child: a case report w...
Abstract Background Temporalis muscle hypertrophy is a rare entity of masticatory muscle hypertrophy. All types of masticatory muscle hypertrophies have been documented of which... -
Arginase impairs hypoxic pulmonary vasoconstriction in murine endotoxemia
Abstract Background Hypoxic pulmonary vasoconstriction (HPV) optimizes the match between ventilation and perfusion in the lung by reducing blood flow to poorly ventilated... -
Does growth hormone supplementation improve oocyte competence and IVF outcome...
Abstract Background Many studies have demonstrated the benefits of the addition of growth hormone (GH) to the controlled ovarian stimulation protocol in vitro fertilization... -
Randomized controlled studies on the efficacy of antiarthritic agents in inhi...
Abstract Background As an initial step in the development of a local therapeutic to treat osteoarthritis (OA), a number of agents were tested for their ability to block... -
Leptin receptor signaling is required for high-fat diet-induced atrophic gast...
Abstract Background Obesity increases the risk for malignancies in various tissues including the stomach. Atrophic gastritis with precancerous lesions is an obesity-associated... -
Neuropsychological profiles of adult bipolar disorder patients with and witho...
Abstract Background Comorbid attention-deficit/hyperactivity disorder (ADHD) is common in bipolar disorder and associated with worse outcomes. Cognitive testing might be a tool... -
Developmental basis for intestinal barrier against the toxicity of graphene o...
Abstract Background Intestinal barrier is crucial for animals against translocation of engineered nanomaterials (ENMs) into secondary targeted organs. However, the molecular...
