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Burden of onchocerciasis-associated epilepsy: First estimates and research pr...
Abstract Background Since the 1990s, evidence has accumulated of an increased prevalence of epilepsy in onchocerciasis-endemic areas in Africa as compared to onchocerciasis-free... -
Communication around HPV vaccination for adolescents in low- and middle-incom...
Abstract Background: Human papillomavirus (HPV) infection causes cervical cancer. More than 80% of those diagnosed with cervical cancer live in low- and middle-income countries... -
Development of an infant feeding core outcome set for childhood obesity inter...
Abstract Background Childhood obesity is a significant public health challenge that affects approximately one in five children worldwide. Infant feeding practices are implicated... -
The efficacy of varenicline in achieving abstinence among waterpipe tobacco s...
Abstract Background Waterpipe tobacco smoking has increased among youth across the globe including in the US, and it continues as a common and traditional form of smoking... -
Combined interventions to reduce HIV incidence in KwaZulu-Natal: a modelling ...
Abstract Background Combined prevention interventions, including early antiretroviral therapy initiation, may substantially reduce HIV incidence in hyperendemic settings. Our... -
Prioritising pathogens for the management of severe febrile patients to impro...
Abstract Background Severe febrile illness without a known source (SFWS) is a challenge for clinicians when deciding how to manage a patient, particularly given the wide... -
Immune responses upon Campylobacter jejuni infection of secondary abiotic mic...
Abstract Background Campylobacter jejuni infections are of rising importance worldwide. Given that innate immune receptors including nucleotide-oligomerization-domain-2 (Nod2)... -
Transient detectable viremia and the risk of viral rebound in patients from t...
Abstract Background Temporary increases in plasma HIV RNA ('blips') are common in HIV patients on combination antiretroviral therapy (cART). Blips above 500 copies/mL have been... -
Specificity versus redundancy in the RAP2.4 transcription factor family of Ar...
Abstract Background The Arabidopsis ERFIb / RAP2.4 transcription factor family consists of eight members with highly conserved DNA binding domains. Selected members have been... -
Predictors of delayed culture conversion among Ugandan patients
Abstract Background Estimates of month-2 culture conversion, a proxy indicator of tuberculosis (TB) treatment efficacy in phase-2 trials can vary by culture-type and... -
Comparative efficacy between atorvastatin and rosuvastatin in the prevention ...
© 2019 The Author(s). Background: There is no randomized clinical trials with recurrence of atherosclerotic cardiovascular disease (ASCVD) as a major outcome with rosuvastatin.... -
Fetal sex and maternal pregnancy outcomes: a systematic review and meta-analysis
Abstract Background Since the placenta also has a sex, fetal sex–specific differences in the occurrence of placenta-mediated complications could exist. Objective To determine... -
Acute ileitis facilitates infection with multidrug resistant Pseudomonas aeru...
Abstract Background The rising incidence of multidrug resistant (MDR) Gram-negative bacteria including Pseudomonas aeruginosa has become a serious issue in prevention of its... -
Occurrence of marked sepsis-induced immunosuppression in pediatric septic sho...
Abstract Background While the process of sepsis-induced immunosuppression is now well described in adults, very little information is available on immune functions in pediatric... -
The effectiveness of shared decision-making followed by positive reinforcemen...
Abstract Background Although the recovery of patients suffering from low back pain is highly context dependent, patient preferences about treatment options are seldom... -
The cost of influenza-associated hospitalizations and outpatient visits in Kenya
Background: We estimated the cost-per-episode and the annual economic burden associated with influenza in Kenya. Methods: From July 2013–August 2014, we recruited patients with... -
Pressure pain thresholds over the cranio-cervical region in headache: a syste...
Abstract Background Sensitivity of tissues can be measured by algometry. Decreased pressure pain thresholds over the cranio-cervical area are supposed to reflect signs of... -
Negligible risk of inducing resistance in Mycobacterium tuberculosis with sin...
Abstract Post-exposure prophylaxis (PEP) for leprosy is administered as one single dose of rifampicin (SDR) to the contacts of newly diagnosed leprosy patients. SDR reduces the... -
Potential impact of multiple interventions on HIV incidence in a hyperendemic...
Abstract Background Multiple prevention interventions, including early antiretroviral therapy initiation, may reduce HIV incidence in hyperendemic settings. Our aim was to... -
dedup_wf_001--2e0bc162b122a3d566233f9782f6ecde
Increased vaccine hesitancy presents challenges to public health and undermines efforts to eradicate diseases such as measles, rubella, and polio. The decline is partly...
