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Managing sequence-dependent setup times - The target conflict between output ...
Sequence-dependent setup times cause a trade-off between output rate, WIP and fluctuating throughput times. Companies usually face this trade-off by bundling similar orders in... -
The impairment of small nerve fibers in severe sepsis and septic shock
Abstract Background A decrease of small nerve fibers in skin biopsies during the course of critical illness has been demonstrated recently. However, the diagnostic use of skin... -
Increasing the treatment motivation of patients with somatic symptom disorder...
Abstract Background Therapeutic intervention programs for somatic symptom disorder (SSD) show only small-to-moderate effect sizes. These effects are partly explained by the... -
A randomised, double-blind clinical phase II trial of the efficacy, safety, t...
Abstract Background The clinical development of a single encounter treatment for uncomplicated malaria has the potential to significantly improve the effectiveness of...