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Open-label, multicenter, single-arm phase II DeCOG-study of ipilimumab in pre...
Abstract Background Ipilimumab is an approved immunotherapy that has shown an overall survival benefit in patients with cutaneous metastatic melanoma in two phase III trials. As... -
CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development
Abstract Background Single nucleotide polymorphisms (SNPs) in chitinase 3-like 1 (CHI3L1), the gene encoding YKL-40, and increased serum YKL-40 levels are associated with severe... -
Long-term safety and efficacy of vismodegib in patients with advanced basal c...
Abstract Background In the primary analysis of the ERIVANCE BCC trial, vismodegib, the first US Food and Drug Administration–approved Hedgehog pathway inhibitor, showed... -
A randomised, double-blind clinical phase II trial of the efficacy, safety, t...
Abstract Background The clinical development of a single encounter treatment for uncomplicated malaria has the potential to significantly improve the effectiveness of...
